Services
Variation Interpretation Tools
PON-All
Pathogenicity prediction of amino amino acid substitutions in any organism. |
PON-BTK
Method for classifying variations in the kinase domain of Bruton tyrosine kinase (BTK) related to X-linked agammaglobulinemia (XLA). |
PON-Diso
Predictor for changes in protein disorder status caused by amino acid substitutions. |
PON-Fold
Prediction method for folding effects of aminoi acid substitutions. |
PON-IDR
Predictor for pathogenicity of variations within intrinsically disordered regions and proteins. |
PON-MMR2
Predictor for the pathogenicity of amino acid substitutions in mismatch repair (MMR) proteins (MLH1, MSH2, MSH6 and PMS2). |
PON-mt-tRNA
Prediction method for the pathogenicity of single nucleotide substitutions in human mitochondrial tRNAs. |
PON-P3
Predictor for the pathogenicity of amino acid substitutions. |
PON-Sol2
Prediction method for the impact of amino acid substitutions on protein solubility. |
PON-Del
PON-Del predictor for short protein deletions. |
ProToxin
ProToxin is a machine learning-based predictor for detecting protein toxins from sequences. |
Prediction methods
ProTstab2
Predictor for protein stability as indicated by melting temperature (Tm). |
SolAcc
Tool to predict relative solvent accessibilityof proteins based on sequence information. |
Other resources
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B-Cell Proteome
Databse for proteomics studies of B cell differentiation. |
PID classification
Systematic classification of primary immunodeficiencies based on clinical, pathological and laboratory parameters. |
VariO
Variation Ontology is an ontology for standardized, systematic description of effects, consequences and mechanisms of variations. |