Mannose-binding lectin deficiency

Mannose binding lectin protein is a member of collectin family and important for innate immunity. MBL-deficiency has been related to a number of diseases. MBL deficiency mainly results from three mutations in exon 1 of the gene and is associated with both increased susceptibility to infections and autoimmune disease.

Alternative names

Mannan-binding protein deficiency


  • Complement regulatory proteins
    • Mannose-binding lectin deficiency


Autosomal recessive/Autosomal dominant