Printable factfile
Gene Information
Names
HUGO name: G6PD
Alias(es):
- G6PD1
- Glucose-6-phosphate dehydrogenase
- Glucose-6-phosphate 1-dehydrogenase
Localization
Reference sequences
Chromosomal location
Maps
Variations / Mutations
Other gene-based resources
Protein Information
Description
Protein function:
Produces pentose sugars for nucleic acid synthesis and main producer of NADPH reducing power.
Catalytic activity:
D-glucose 6-phosphate + NADPH(+) = d-glucono-1,5-lactone 6-phosphate + NADPH.
Subunit:
Homodimer or homotetramer.
Alternative products:
2 isoforms; a long form and short form; are produced by alternative splicing. The isoforms are found in different tissues.
Pathway:
Pentose phosphate pathway.
Other features
Other related resourses:
Expression
Expression pattern for human
| Tissue | Expression (%) | Clones |
|---|---|---|
| eye, cornea | 11.72 | 1:451 |
| leukopheresis | 8.12 | 7:4557 |
| whole blood | 6.48 | 3:2445 |
| lung, cell line | 6.03 | 1:876 |
| blood, white cells | 5.81 | 1:910 |
| B cells from burkitt lymphoma | 4.93 | 2:2143 |
| T cells from T cell leukemia | 4.41 | 2:2397 |
| esophagus | 3.58 | 2:2949 |
| blood | 3.34 | 8:12646 |
| leukocyte | 2.94 | 5:8982 |