IgA deficiency

Many individuals with IgA deficiency are asymptomatic. Patients with IgA deficiency have an increased incidence of upper respiratory tract infections, allergies and autoimmune disease like SLE, rheumatoid arthritis, and juvenile chronic arthritis. Others have persistent or recurrent infections and some develop CVI over time. Also, there is a possibility of transfusion reaction due to anti-IgA antibodies. Malignancy may be increased.

Therapeutic options