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- databases for immunodeficiency-causing variations

   STAT3base
   Variation registry for  Hyper-IgE syndrome


Aminoacid substitutions - STAT3base

 - indicates amino acid change that require more complex mutation than single nucleotide substitution.
Aminoacid substitutions
Hydrophilic
HydrophobicAcidicBasicPolarSpecial
--> AFILMVWYDEHKRNQSTCGPTotal
A ------------0
F -2-1--------1---4
I ----------0
L ---------0
M --------------0
V 111-----------12
W ---------------0
Y -----------2--2
D ------------0
E -------3-----1-4
H ------4------26
K -------1-----1
R --1-19----21243
N ------3------3
Q -------------11
S 1------1-2
T -3--------1--4
C -------------0
G -----1------1
P 1------------1
Total 2034111194410301212023384
Aminoacid substitutions (%)
Hydrophilic
HydrophobicAcidicBasicPolarSpecial
--> AFILMVWYDEHKRNQSTCGPTotal
A ------------0.0
F -2.4-1.2--------1.2---4.8
I ----------0.0
L ---------0.0
M --------------0.0
V 1.213.1-----------14.3
W ---------------0.0
Y -----------2.4--2.4
D ------------0.0
E -------3.6-----1.2-4.8
H ------4.8------2.47.1
K -------1.2-----1.2
R --1.2-22.6----25.02.451.2
N ------3.6------3.6
Q -------------1.21.2
S 1.2------1.2-2.4
T -3.6--------1.2--4.8
C -------------0.0
G -----1.2------1.2
P 1.2------------1.2
Total 2.40.03.64.813.11.222.64.84.81.20.03.60.01.225.02.40.02.43.63.6100.0