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 - databases for immunodeficiency-causing variations

   SH2D1Abase
   Variation registry for  X-linked lymphoproliferative syndrome (XLP)


Aminoacid substitutions - SH2D1Abase

 - indicates amino acid change that require more complex mutation than single nucleotide substitution.
Aminoacid substitutions
Hydrophilic
HydrophobicAcidicBasicPolarSpecial
--> AFILMVWYDEHKRNQSTCGPTotal
A ------------0
F ----------3---3
I -------6---6
L ---------11
M --1------------1
V ----------1-1
W ---------------0
Y -----------3--3
D -----1-------1
E ------31-------4
H ------1------12
K ------------0
R --1-----12
N ------------0
Q -------------11
S ------2-24
T -1-------1---2
C -----1--------1
G ----1-2----1--4
P --1----------1
Total 0022011161003004733337
Aminoacid substitutions (%)
Hydrophilic
HydrophobicAcidicBasicPolarSpecial
--> AFILMVWYDEHKRNQSTCGPTotal
A ------------0.0
F ----------8.1---8.1
I -------16.2---16.2
L ---------2.72.7
M --2.7------------2.7
V ----------2.7-2.7
W ---------------0.0
Y -----------8.1--8.1
D -----2.7-------2.7
E ------8.12.7-------10.8
H ------2.7------2.75.4
K ------------0.0
R --2.7-----2.75.4
N ------------0.0
Q -------------2.72.7
S ------5.4-5.410.8
T -2.7-------2.7---5.4
C -----2.7--------2.7
G ----2.7-5.4----2.7--10.8
P --2.7----------2.7
Total 0.00.05.45.40.02.72.72.716.22.70.00.08.10.00.010.818.98.18.18.1100.0