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 - databases for immunodeficiency-causing variations

   PRF1base
   Variation registry for  Familial haemophagocytic lymphohistiocytosis, type II (FHL2)


Aminoacid substitutions - PRF1base

 - indicates amino acid change that require more complex mutation than single nucleotide substitution.
Aminoacid substitutions
Hydrophilic
HydrophobicAcidicBasicPolarSpecial
--> AFILMVWYDEHKRNQSTCGPTotal
A ----33--2------35
F -1-1---------2--4
I ------2----2
L ---------0
M --4-1-----------5
V 5----------1-6
W -----------2----2
Y -------------0
D -----2--1-----3
E -------2------2
H --------110----11
K ------------0
R ---12---9-52129
N ---------4---4
Q -------------33
S ------2-2
T -1-8---------9
C -1----1----1----3
G -----12--5--26--34
P 1--6------1--7--15
Total 11571335123321029510307734169
Aminoacid substitutions (%)
Hydrophilic
HydrophobicAcidicBasicPolarSpecial
--> AFILMVWYDEHKRNQSTCGPTotal
A ----19.5--1.2------20.7
F -0.6-0.6---------1.2--2.4
I ------1.2----1.2
L ---------0.0
M --2.4-0.6-----------3.0
V 3.0----------0.6-3.6
W -----------1.2----1.2
Y -------------0.0
D -----1.2--0.6-----1.8
E -------1.2------1.2
H --------0.65.9----6.5
K ------------0.0
R ---7.1---5.3-3.01.20.617.2
N ---------2.4---2.4
Q -------------1.81.8
S ------1.2-1.2
T -0.6-4.7---------5.3
C -0.6----0.6----0.6----1.8
G -----0.61.2--3.0--15.4--20.1
P 0.6--3.6------0.6--4.1--8.9
Total 0.60.63.04.17.720.77.11.81.81.25.91.25.33.05.917.84.14.11.82.4100.0