| Original nucleotide | Replacing nucleotide | Number of residues | Number of independent families | Fraction of residues [%] | Fraction of independent families [%] |
| a | c | 21 | 23 | 4.6 | 2.38 |
| a | g | 44 | 75 | 9.63 | 7.76 |
| a | t | 16 | 72 | 3.5 | 7.45 |
| c | a | 31 | 53 | 6.78 | 5.48 |
| c | g | 11 | 13 | 2.41 | 1.34 |
| c | t | 86 | 169 | 18.82 | 17.48 |
| g | a | 89 | 163 | 19.47 | 16.86 |
| g | c | 32 | 78 | 7 | 8.07 |
| g | t | 43 | 142 | 9.41 | 14.68 |
| t | a | 17 | 23 | 3.72 | 2.38 |
| t | c | 46 | 100 | 10.07 | 10.34 |
| t | g | 21 | 56 | 4.6 | 5.79 |
| Original nucleotide | Replacing nucleotide | Fraction of residues [%] | Fraction of independent families [%] |
| a | c | 4.42 | 2.29 |
| a | g | 9.27 | 7.46 |
| a | t | 3.37 | 7.17 |
| c | a | 7.16 | 5.78 |
| c | g | 2.54 | 1.42 |
| c | t | 19.86 | 18.44 |
| g | a | 20.73 | 17.95 |
| g | c | 7.45 | 8.59 |
| g | t | 10.02 | 15.63 |
| t | a | 3.41 | 2.18 |
| t | c | 9.24 | 9.49 |
| t | g | 4.22 | 5.32 |
| Nucleotide | Number of nucleotide | Fraction of nucleotide [%] |
| A | 29324 | 24 |
| C | 32151 | 26 |
| G | 32441 | 27 |
| T | 27971 | 23 |
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