Database        IDdiagnostics
Version         1.53
File            IDdiags.html
Date            06-Oct-1999 (Created)
Date            08-Oct-2008 (Last updated)
Curator         Mauno Vihinen
Address         Institute of Medical Technology, University of Tampere, 
Address         FIN-33014 Tampere, Finland
Phone           +358-3-215 7735
Fax             +358-3-215 7710
Email           Mauno.Vihinen@uta.fi
Maintainer      Crina Samarghitean   
Address         Institute of Medical Technology, University of Tampere, 
Address         FIN-33014 Tampere, Finland
Phone           +358-3-215 8915  
Fax             +358-3-215 8915 
Email           Crina.Samarghitean@uta.fi
Funding         Finnish Academy, European Union, 
Funding         Tampere University Hospital Medical Research 
URL             http://structure.bmc.lu.se/idbase/IDdiagnostics/
FTP             ftp://protein.uta.fi/pub/iddiags.dat
//
Disease         X-linked agammaglobulinemia (XLA)
Accession       I0008
Date            02-Nov-1999 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF22.xml
OMIM            300300
Gene            BTK
IDbase          BTKbase
Contact         Dr. Rik. A. Brooimans
Address         Wilhelmina Children's Hospital Dept. of Immunology
Address         Lundlaan 6, 3584 EA Utrecht, The Netherlands
Telephone       +31-302504354
Fax             +31-302505311
Email           r.brooimans@wkz.azu.nl
Method          Direct sequencing
Turnaround      1 month
Samples         8
//
Disease         Wiskott-Aldrich syndrome and X-linked thrombocytopenia
Accession       I0009
Date            17-Dec-1999 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF71.xml
OMIM            300392
Gene            WAS
IDbase          WASbase
Contact         Dr. M. Losekoot
Address         Dept. of Human and Clinical Genetics, DNA-diagnostic 
Address         section
Address         Leiden University Medical Centre, The Netherlands 
Telephone       +31-071-5276082
Fax             +31-071-5271601
Email           m.losekoot@kgc.azl.nl
Method          Direct sequencing
Frequency       2 cases/year
Turnaround      3 months
Samples         2 samples/year
Price           About 500 EUR
//
Disease         RAG1 deficiency
Accession       I0022
Date            27-Dec-1999 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF2.xml
OMIM            179615
Gene            RAG1
IDbase          RAG1base 
Contact         Dr. Anna Villa
Address         CNR-ITB Via Fratelli Cervi 93, 20090 Segrate (MI), Italy
Telephone       +39-02-26422636
Fax             +39-02-26422660
Email           anna.villa@itb.cnr.it
URL             www.itba.mi.cnr.it
Method          Direct sequencing
Frequency       Weekly
Turnaround      1 month
Samples         20
Price           Free 
//
Disease         RAG2 deficiency
Accession       I0023
Date            27-Dec-1999 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF3.xml
OMIM            179616
Gene            RAG2
IDbase          RAG2base
Contact         Dr. Anna Villa
Address         CNR-ITB Via Fratelli Cervi 93, 20090 Segrate (MI), Italy
Telephone       +39-02-26422636
Fax             +39-02-26422660
Email           anna.villa@itb.cnr.it
URL             www.itba.mi.cnr.it
Method          Direct sequencing
Frequency       Weekly
Samples         20
Price           Free 
//
Disease         CD3gamma deficiency
Accession       I0024
Date            19-Jan-2000 (Rel. 1, Created)
Date            10-Mar-2006 (Last updated)
IDR fact file   FF21.xml
OMIM            186740
Gene            CD3G
IDbase          CD3Gbase
Contact         Dr. Jose R. Regueiro
Address         Inmunologia, Facultad De Medicina, Universidad
Address         Complutense de Madrid, 28040 Madrid, Spain
Telephone       +34 913 941 642
Fax             +34 913 941 641
Email           regueiro@med.ucm.es
URL             http://www.ucm.es/info/inmuno/regueiro.htm
Method          Direct sequencing, CD3 haplotype segregation
Frequency       Seldom
Turnaround      1 month
Samples         3/year
Price           300 EUR
Comment         A TCR/CD3 expression impairment in otherwise 
Comment         phenotypically normal (CD2+)CD4+ and CD8 bright T 
Comment         lymphocytes, or a severe T lymphocytopenia should be
Comment         ascertained.
//
Disease         X-linked hyper-IgM syndrome (CD40L deficiency)
Accession       I0025
Date            23-Mar-2000 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF16.xml
OMIM            308230
Gene            TNFSF5
IDbase          TNFSF5base
Contact         Dr. Ma. Cruz Garcia Rodriguez
Address         Unidad de Inmunologia, Hospital La Paz, Paseo de 
Address         la Castellana 261, 28046 Madrid, Spain
Telephone       +34-91-7277095
Fax             +34-91-7277095
Email           mcruzgarcia@hulp.insalud.es
Method          SSCP, Direct sequencing
Frequency       Whenever required
Samples         2 samples per year
Prices          300 EUR/patient 112/carrier
Comment         Patient samples are only accepted for analysis after 
Comment         prior consultation and submission of clinical and 
Comment         laboratory data. Fresh blood wanted.
//
Disease         X-linked agammaglobulinemia (XLA)
Accession       I0026
Date            23-Mar-2000 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF22.xml
OMIM            300300
Gene            BTK
IDbase          BTKbase
Contact         Dr. Ma. Cruz Garcia Rodriguez
Address         Unidad de Inmunologia, Hospital  Universitario La 
Address         Paz, Paseo de la Castellana 261, 28046 Madrid, Spain
Telephone       +34-91-7277095
Fax             +34-91-7277095
Email           mcruzgarcia@hulp.insalud.es
Method          Direct sequencing; SSCP
Frequency       Weekly
Samples         12 patients /year
Prices          482 EUR/patient, 180 EUR/carrier
Comment         Patient samples are only accepted for analysis after 
Comment         prior consultation and submission of clinical and 
Comment         laboratory data. Fresh blood wanted.
Comment         do their molecular diagnosis and family carriers.
//
Disease         X-linked agammaglobulinemia (XLA)
Accession       I0027
Date            24-May-2000 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF22.xml
OMIM            300300
Gene            BTK
IDbase          BTKbase
Contact         Prof. J.J.M. van Dongen
Address         Dept.of Immunology, Erasmus University Rotterdam, POB 1738
Address         3000 DR Rotterdam, The Netherlands
Telephone       +31-10-4088094
Fax             +31-10-4089456
Email           vandongen@immu.fgg.eur.nl
Method          Direct sequencing; SSCP + Heteroduplex analysis
Frequency       2 per week
Turnaround      3 months
Price           550 EUR per gene
Comment         Patient samples are only accepted for analysis after 
Comment         prior consultation and exchance of clinical and 
Comment         laboratory data. Fresh blood wanted.
//
Disease         X-linked hyper-IgM syndrome (CD40L deficiency)
Accession       I0028
Date            24-May-2000 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF16.xml
OMIM            308230
Gene            TNFSF5
IDbase          TNFSF5base
Contact         Prof. J.J.M. van Dongen
Address         Dept.of Immunology, Erasmus University Rotterdam, POB 1738
Address         3000 DR Rotterdam, The Netherlands
Telephone       +31-10-4088094
Fax             +31-10-4089456
Email           vandongen@immu.fgg.eur.nl
Method          Direct sequencing; SSCP + Heteroduplex analysis
Frequency       2 per week
Turnaround      3 months
Price           550 EUR per gene
Comment         Patient samples are only accepted for analysis after prior
Comment         consultation and exchange of clinical and laboratory data.
Comment         Fresh blood wanted.
//
Disease         X-linked SCID(gammac-chain deficiency)
Accession       I0029
Date            24-May-2000 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF8.xml
OMIM            300400
Gene            IL2RG
IDbase          IL2RGbase
Contact         Prof. J.J.M. van Dongen
Address         Dept.of Immunology, Erasmus University Rotterdam, POB 1738
Address         3000 DR Rotterdam, The Netherlands
Telephone       +31-10-4088094
Fax             +31-10-4089456
Email           vandongen@immu.fgg.eur.nl
Method          Direct sequencing; SSCP + Heteroduplex analysis
Frequency       2 per week
Turnaround      3 months
Price           550 EUR per gene
Comment         Patient samples are only accepted for analysis after prior
Comment         consultation and exchange of clinical and laboratory data.
Comment         Fresh blood wanted.
//
Disease         JAK3 deficiency
Accession       I0030
Date            24-May-2000 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF9.xml
OMIM            600173
Gene            JAK3
IDbase          JAK3base
Contact         Prof. J.J.M. van Dongen
Address         Dept.of Immunology, Erasmus University Rotterdam, POB 1738
Address         3000 DR Rotterdam, The Netherlands
Telephone       +31-10-4088094
Fax             +31-10-4089456
Email           vandongen@immu.fgg.eur.nl
Method          Direct sequencing; SSCP + Heteroduplex analysis
Frequency       2 per week
Turnaround      3 months
Price           550 EUR per gene
Comment         Patient samples are only accepted for analysis after prior
Comment         consultation and exchange of clinical and laboratory data.
Comment         Fresh blood wanted.
//
Disease         RAG1 deficiency
Accession       I0031
Date            24-May-2000 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF2.xml
OMIM            179615
Gene            RAG1
IDbase          RAG1base
Contact         Prof. J.J.M. van Dongen
Address         Dept.of Immunology, Erasmus University Rotterdam, POB 1738
Address         3000 DR Rotterdam, The Netherlands
Telephone       +31-10-4088094
Fax             +31-10-4089456
Email           vandongen@immu.fgg.eur.nl
Method          Direct sequencing; SSCP + Heteroduplex analysis
Frequency       2 per week
Turnaround      3 months
Price           550 EUR per gene
Comment         Patient samples are only accepted for analysis after prior
Comment         consultation and exchange of clinical and laboratory data.
Comment         Fresh blood wanted.
//
Disease         RAG2 deficiency
Accession       I0032
Date            24-May-2000 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF3.xml
OMIM            179616
Gene            RAG2
IDbase          RAG2base
Contact         Prof. J.J.M. van Dongen
Address         Dept.of Immunology, Erasmus University Rotterdam, POB 1738
Address         3000 DR Rotterdam, The Netherlands
Telephone       +31-10-4088094
Fax             +31-10-4089456
Email           vandongen@immu.fgg.eur.nl
Method          Direct sequencing; SSCP + Heteroduplex analysis
Frequency       2 per week
Turnaround      3 months
Price           550 EUR per gene
Comment         Patient samples are only accepted for analysis after prior
Comment         consultation and exchange of clinical and laboratory data.
Comment         Fresh blood wanted
//
Disease         Wiskott-Aldrich syndrome and X-linked thrombocytopenia
Accession       I0033
Date            24-May-2000 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF71.xml
OMIM            300392
Gene            WAS
IDbase          WASbase
Contact         Prof. J.J.M. van Dongen
Address         Dept.of Immunology, Erasmus University Rotterdam, POB 1738
Address         3000 DR Rotterdam, The Netherlands
Telephone       +31-10-4088094
Fax             +31-10-4089456
Email           vandongen@immu.fgg.eur.nl
Method          Direct sequencing; SSCP + Heteroduplex analysis
Frequency       2 per week
Turnaround      3 months
Price           550 EUR per gene
Comment         Patient samples are only accepted for analysis after prior
Comment         consultation and exchange of clinical and laboratory data.
Comment         Fresh blood wanted.
//
Disease         Kappa  light chain deficiency
Accession       I0034
Date            24-May-2000 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF65.xml
OMIM            147200
Gene            IGKC
IDbase          IL2RGbase
Contact         Prof. J.J.M. van Dongen
Address         Dept.of Immunology, Erasmus University Rotterdam, POB 1738
Address         3000 DR Rotterdam, The Netherlands
Telephone       +31-10-4088094
Fax             +31-10-4089456
Email           vandongen@immu.fgg.eur.nl
Method          Direct sequencing; SSCP + Heteroduplex analysis
Frequency       2 per week
Turnaround      3 months
Price           550 EUR per gene
Comment         Patient samples are only accepted for analysis after prior
Comment         consultation and exchange of clinical and laboratory data.
Comment         Fresh blood wanted.
//
Disease         Ig heavy chain deletion
Accession       I0035
Date            24-May-2000 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF27.xml
OMIM            147020
Gene            IGLL1
IDbase          IGLL1base
Contact         Prof. J.J.M. van Dongen
Address         Dept.of Immunology, Erasmus University Rotterdam, POB 1738
Address         3000 DR Rotterdam, The Netherlands
Telephone       +31-10-4088094
Fax             +31-10-4089456
Method          Direct sequencing; SSCP + Heteroduplex analysis
Frequency       2 per week
Turnaround      3 months
Price           550 EUR per gene
Comment         Patient samples are only accepted for analysis after prior
Comment         consultation and exchange of clinical and laboratory data.
Comment         Fresh blood wanted.
//
Disease         IFNgamma-receptor 1 deficiency
Accession       I0036
Date            24-May-2000 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF44.xml
OMIM            107470
Gene            IFNGR1
IDbase          IFNGR1base
Contact         Prof. J.J.M. van Dongen
Address         Dept.of Immunology, Erasmus University Rotterdam, POB 1738
Address         3000 DR Rotterdam, The Netherlands
Telephone       +31-10-4088094
Fax             +31-10-4089456
Price           550 EUR per gene
Method          Direct sequencing; SSCP + Heteroduplex analysis
Frequency       2 per week
Turnaround      3 months
Price           550 EUR per gene
Comment         Patient samples are only accepted for analysis after prior
Comment         consultation and exchange of clinical and laboratory data.
Comment         Fresh blood wanted.
//
Disease         ALPS type Ia (defective CD95)
Accession       I0037
Date            24-May-2000 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF36.xml
OMIM            601859
Gene            TNFRSF6
IDbase          TNFRSF6base
Contact         Prof. J.J.M. van Dongen
Address         Dept.of Immunology, Erasmus University Rotterdam, POB 1738
Address         3000 DR Rotterdam, The Netherlands
Telephone       +31-10-4088094
Fax             +31-10-4089456
Method          Direct sequencing; SSCP + Heteroduplex analysis
Frequency       2 per week
Turnaround      3 months
Price           550 EUR per gene
Comment         Patient samples are only accepted for analysis after prior
Comment         consultation and exchange of clinical and laboratory data.
Comment         Fresh blood wanted.
//
Disease         X-linked chronic granulomatous disease
Accession       I0038
Date            30-May-2000 (Rel. 1, Created)
Date            31-Aug-2006 (Last updated)
IDR fact file   FF38.xml
OMIM            300481
Gene            CYBB
IDbase          CYBBbase
Contact         Prof. Dirk Roos
Address         Sanquin Research, Plemanlaan 125, 1066CX Amsterdam,
Address         Netherlands
Telephone       31-20-5123377
Fax             31-20-5123474
Email           d.roos@sanquin.nl
Method          Direct sequencing
Frequency       6 times per year
Turnaround      about 4 weeks
Samples         about 30
Price           550 Euro
Comment         Only after consultation by email. Needed: purified DNA from
Comment         EDTA blood or from citrate blood, NOT from heparin blood.
Comment         Preferably also Western Blot to establish X-CGD
//
Disease         Autosomal recessive CGD p47 phox
Accession       I0039
Date            30-May-2000 (Rel. 1, Created)
Date            31-Aug-2006 (Last updated)
IDR fact file   FF40.xml
OMIM            608512
Gene            NCF1
IDbase          NCF1base
Contact         Prof. Dirk Roos
Address         Sanquin Research, Plemanlaan 125, 1066CX Amsterdam,
Address         Netherlands
Telephone       31-20-5123377
Fax             31-20-5123474
Email           d.roos@sanquin.nl
Method          Other; gene scan
Frequency       on request
Turnaround      about 2 weeks
Samples         about 20 per year
Price           550 Euro
Comment         Only after consultation by email. Needed: purified DNA from
Comment         EDTA blood or from citrate blood, NOT from heparin blood.
Comment         Preferably also Western Blot to establish p47-CGD.
//
Disease         Autosomal recessive CGD p22 phox
Accession       I0040
Date            30-May-2000 (Rel. 1, Created)
Date            31-Aug-2006 (Last updated)
IDR fact file   FF39.xml
OMIM            608508
Gene            CYBA
IDbase          CYBAbase
Contact         Prof. Dirk Roos
Address         Sanquin Research, Plemanlaan 125, 1066CX Amsterdam,
Address         Netherlands
Telephone       31-20-5123377
Fax             31-20-5123474
Email           d.roos@sanquin.nl
Method          Direct sequencing
Frequency       on request
Turnaround      about 4 weeks
Samples         3-5 per year
Price           550 Euro
Comment         Only after consultation by email. Needed: purified DNA from
Comment         EDTA blood or from citrate blood, NOT from heparin blood.
Comment         Preferably also Western Blot to establish p22-CGD.
//
Disease         Autosomal recessive CGD p67 phox
Accession       I0041
Date            30-May-2000 (Rel. 1, Created)
Date            31-Aug-2006 (Last updated)
IDR fact file   FF41.xml
OMIM            608515
Gene            NCF2
IDbase          NCF2base
Contact         Prof. Dirk Roos
Address         Sanquin Research, Plemanlaan 125, 1066CX Amsterdam,
Address         Netherlands
Telephone       31-20-5123377
Fax             31-20-5123474
Email           d.roos@sanquin.nl
Method          Direct sequencing
Frequency       on request
Turnaround      about 4 weeks
Samples         3-5 per year
Price           550 Euro
Comment         Only after consultation by email. Needed: purified DNA from
Comment         EDTA blood or from citrate blood, NOT from heparin blood.
Comment         Preferably also Western Blot to establish p67-CGD.
//
Disease         Leukocyte adhesion deficiency 1
Accession       I0042
Date            30-May-2000 (Rel. 1, Created)
Date            31-Aug-2006 (Last updated)
IDR fact file   FF42.xml
OMIM            600065
Gene            ITGB2
IDbase          ITGB2base
Contact         Prof. Dirk Roos
Address         Sanquin Research, Plemanlaan 125, 1066CX Amsterdam,
Address         Netherlands
Telephone       31-20-5123377
Fax             31-20-5123474
Email           d.roos@sanquin.nl
Method          Direct sequencing
Frequency       on request
Turnaround      about 4 weeks
Samples         2-3 per year
Price           550 Euro
Comment         Only after consultation by email. Needed: purified DNA from
Comment         EDTA blood or from citrate blood, NOT from heparin blood.
Comment         FACS analysis to establish LAD-1.
//
Disease         Wiskott-Aldrich syndrome and X-linked thrombocytopenia
Accession       I0044
Date            20-Nov-2000 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF71.xml
OMIM            300392
Gene            WAS
IDbase          WASbase
Contact         Dr. Alfons Meindl
Address         Abt. fur Med. Genetik der LMU Muenchen Goethestr. 
Address         29, 80336 Muenchen, Germany
Telephone       +089-5160-4467
Fax             +089-5160-4780
Email           alfons@pedgen.med.uni-muenchen.de
Contact         Dr. M. Albert/Prof. B. Belohradsky
Address         Dr. V. Haunersches, Kinderspital der LMU Muenchen,  
Address         Lindwurmstr. 4, 80337 Muenchen, Germany
Telephone       +089-5160-2811
Fax             +089-5160-7743
Email           michael.albert@kk-i.med.uni.muenchen.de
Method          Direct sequencing
Frequency       20 / year
Turnaround      2 - 4 weeks
Samples         40 / year
Price           Subject to inquiry
//
Disease         X-linked lymphoproliferative syndrome(Duncan disease)
Accession       I0045
Date            20-Nov-2000 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF73.xml
OMIM            308240
Gene            SH2D1A
IDbase          SH2D1Abase
Contact         Dr. Alfons Meindl
Address         Abt. fur Med. Genetik der LMU Muenchen, 
Address         Goethestr. 29, 80336 Muenchen, Germany
Telephone       +089-5160-4467
Fax             +089-5160-4780
Email           alfons@pedgen.med.uni-muenchen.de
Contact         Dr. M. Albert/Prof. B. Belohradsky
Address         Dr. V. Haunersches, Kinderspital der LMU Muenchen,  
Address         Lindwurmstr. 4, 80337 Muenchen, Germany
Telephone       +089-5160-2811
Fax             +089-5160-7743
Email           michael.albert@kk-i.med.uni.muenchen.de
Method          Direct sequencing
Frequency       5 / year
Turnaround      2 - 4 weeks
Samples         10 / year
Price           Subject to inquiry
//
Disease         X-linked agammaglobulinemia (XLA)
Accession       I0046
Date            20-Nov-2000 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF22.xml
OMIM            300300
Gene            BTK
IDbase          BTKbase
Contact         Dr. Alfons Meindl
Address         Abt. fur Med. Genetik der LMU Muenchen, 
Address         Goethestr. 29, 80336 Muenchen, Germany
Telephone       +089-5160-4467
Fax             +089-5160-4780
Email           alfons@pedgen.med.uni-muenchen.de
Contact         Dr. M. Albert/Prof. B. Belohradsky
Address         Dr. V. Haunersches, Kinderspital der LMU Muenchen,  
Address         Lindwurmstr. 4, 80337 Muenchen, Germany
Telephone       +089-5160-2811
Fax             +089-5160-7743
Email           michael.albert@kk-i.med.uni.muenchen.de
Method          Direct sequencing
Frequency       20 / year
Turnaround      2 - 4 weeks
Samples         40 / year
Price           Subject to inquiry
//
Disease         Osteopetrosis
Accession       I0047
Date            27-Nov-2000  (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF157.xml
OMIM            604592
Gene            TCIRG1
IDbase          TCIRG1base
Contact         Dr. Anna Villa
Address         ITBA, via Cervi 93, 20090 Segrate (MI), Italy
Telephone       +39-02-26422636
Fax             +39-02-26422660
Email           villa@itba.mi.cnr.it
Method          Direct sequencing; SSCP
Frequency       Every day
Turnaround      Around 1 per week
Samples         Over 30
//
Disease         ZAP70 deficiency
Accession       I0048
Date            28-Nov-2000 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF62.xml
OMIM            176947
Gene            ZAP70
IDbase          ZAP70base
Contact         Dr. Naomi Taylor
Address         Institut de Genetique Moleculaire, 1919 Route de 
Address         Mende, Montpellier, 34293 France
Telephone       +33-4-67613628
Fax             +33-4-67040231
Email           taylor@igm.cnrs-mop.fr
Method          Direct sequencing; Western blot analysis
Frequency       On demand
Turnaround      1 week for blot
Samples         5
Price           None
Comment         Most patients with ZAP-70 deficiency can be 
Comment         identified by a lack of protein expression.
//
Disease         p56 Lck deficiency
Accession       I0049
Date            28-Nov-2000 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF137.xml
OMIM            153390
Gene            LCK
Contact         Dr. Naomi Taylor
Address         Institut de Genetique Moleculaire, 1919 Route de 
Address         Mende, Montpellier, 34293 France
Telephone       +33-4-67613628
Fax             +33-4-67040231
Email           taylor@igm.cnrs-mop.fr
Method          Direct sequencing; Western blot analysis
Frequency       On demand
Turnaround      1 week for blot
Samples         5
Price           None
//
Disease         Wiskott-Aldrich syndrome and X-linked thrombocytopenia
Accession       I0050
Date            05-Apr-2001 (Rel. 1, Created)
Date            19-Oct-2005 (Last updated)
IDR fact file   FF71.xml
OMIM            300392
Gene            WAS
IDbase          WASbase
Contact         Dr. Tadashi Ariga
Address         Dep. of Pediatrics, Hokkaido University Graduate 
Address         School of Medicine, N15, W-7, Kita-ku, Sapporo, 
Address         Japan
Telephone       +81-11-716-1161
Fax             +81-11-706-7898
Email           tada-ari@med.hokudai.ac.jp
Method          Direct sequencing
Frequency       1 per month
Turnaround      1 week
Samples         5-10
Price           Free
//
Disease         lambda5 surrogate light-chain deficiency
Accession       I0051
Date            05-Apr-2001 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF27.xml
OMIM            147020
Gene            IGLL1
IDbase          IGLL1base
Contact         Dr. Lennart Hammarstrom
Address         Klinisk Immunologi,F79 Huddinge University Hospital   
Address         SE-141 86  Stockholm, Sweden
Telephone       +46-8-6089115
Fax             +46-8-58581390
Email           Lennart.Hammarstrom@labmed.ki.se
Method          PFGE
Frequency       On demand
Samples         5-10 per year
Price           Not performed on commercial bases
//
Disease         X-linked chronic granulomatous disease
Accession       I0052
Date            18-May-2001 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF38.xml
OMIM            306400
Gene            CYBB
IDbase          CYBBbase
Contact         Dr. Andrew R Cross
Address         The Scripps Research Institute, MEM-241, 10550,  
Address         North Torrey Pines Road, La Jolla, CA 92037, USA
Telephone       010-858-784-8808
Fax             010-858-784-8890
Email           scross@scripps.edu
Method          Direct sequencing
Frequency       As needed
Turnaround      2-4 weeks
Samples         15 
Price           Shipping cost only
Comment         This analysis is performed on a research basis only. 
//
Disease         Autosomal recessive CGD p22 phox
Accession       I0053
Date            18-May-2001 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF39.xml
OMIM            233690
Gene            CYBA
IDbase          CYBAbase
Contact         Dr. Andrew R Cross
Address         The Scripps Research Institute, MEM-241, 10550,  
Address         North Torrey Pines Road, La Jolla, CA 92037, USA
Telephone       010-858-784-8808
Fax             010-858-784-8890
Email           scross@scripps.edu
Method          Direct sequencing
Frequency       As needed
Turnaround      2-4 weeks
Samples         5 
Price           Shipping cost only
Comment         This analysis is performed on a research basis 
Comment         only.   
//
Disease         Autosomal recessive CGD p47 phox
Accession       I0054
Date            18-May-2001 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF40.xml
OMIM            233700
Gene            NCF1
IDbase          NCF1base
Contact         Dr. Andrew R Cross
Address         The Scripps Research Institute, MEM-241, 10550  
Address         North Torrey Pines Road, La Jolla, CA 92037, USA
Telephone       010-858-784-8808
Fax             010-858-784-8890
Email           scross@scripps.edu
Method          Direct sequencing
Frequency       As needed
Turnaround      2-4 weeks
Samples         15 
Price           Shipping cost only
Comment         This analysis is performed on a research basis only.
//
Disease         Autosomal recessive CGD p67 phox
Accession       I0055
Date            18-May-2001 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF42.xml
OMIM            233710
Gene            NCF2
IDbase          NCF2base
Contact         Dr. Andrew R Cross
Address         The Scripps Research Institute, MEM-241, 10550 
Address         North Torrey Pines Road, La Jolla, CA 92037, USA
Telephone       010-858-784-8808
Fax             010-858-784-8890
Email           scross@scripps.edu
Method          Direct sequencing
Frequency       As needed
Turnaround      2-4 weeks
Samples         5 
Price           Shipping cost only.
Comment         This analysis is performed on a research basis only.  
//
Disease         X-linked agammaglobulinemia
Accession       I0056
Date            18-May-2001 (Rel. 1, Created)
Date            20-Oct-2005 (Last updated)
IDR fact file   FF22.xml
OMIM            300300
Gene            BTK
IDbase          BTKbase
Contact         Dr. Toshio Miyawaki
Address         Department of Pediatrics, Faculty of Medicine, 
Address         University of Toyama, 2630 Sugitani,
Address         Toyama 930-0194, Japan
Telephone       +81-76-434-7310
Fax             +81-76-434-5029
Email           toshio65@ms.toyama-mpu.ac.jp
Method          Direct sequencing; Flow cytometry
Frequency       Daily
Turnaround      2 Days
Samples         40 samples
Price           No charge
Comment         For flow cytometry analysis, 10 ml of heparinized venous 
Comment         blood is required and it should be transferred to the 
Comment         laboratory within a few days.  For PCR-SSCP and direct 
Comment         sequencing, at least 5 micrograms of DNA is required.
//
Disease         X-linked lymphoproliferative syndrome(Duncan disease)
Accession       I0057
Date            18-May-2001 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF73.xml
OMIM            308240
Gene            SH2D1A
IDbase          SH2D1Abase
Contact         Dr. Toshio Miyawaki
Address         Department of Pediatrics, Faculty of Medicine,   
Address         University of Toyama, 2630 Sugitani,
Address         Toyama 930-0194, Japan
Telephone       +81-76-434-7310
Fax             +81-76-434-5029
Email           toshio65@ms.toyama-mpu.ac.jp
Method          Direct sequencing; Flow cytometry
Frequency       Daily
Turnaround      2 days
Samples         20 samples
Price           No charge
Comment         For flow cytometry analysis, 10 ml of haparinized venous 
Comment         blood is required and it should be transferred to the
Comment         laboratory within a few days.  For PCR-SSCP and direct
Comment         sequencing, at least 5 micrograms of DNA is required.
//
Disease         X-linked lymphoproliferative syndrome(Duncan disease)
Accession       I0058
Date            18-May-2001 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF73.xml
OMIM            308240
Gene            SH2D1A
IDbase          SH2D1Abase
Contact         MS. Carrie E Haverty
Address         Center for Human Genetics, 700 Albany Street, Suite 408, 
Address         Boston, MA 02118, USA
Telephone       +617-6387083
Fax             +617-6387092
Email           chaverty@bu.edu
URL             http:www.bumc.bu.edu/hg
Method          Flow cytometry
Frequency       On demand
Turnaround      4 - 6 months
Samples         Around 20 - 25 samples
Price           895 USD
//
Disease         X-linked SCID(gammac-chain deficiency)
Accession       I0059
Date            22-Oct-2001 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF8.xml
OMIM            300400
Gene            IL2RG
IDbase          IL2RGbase
Contact         Dr. Ma. Cruz Garcia Rodriguez
Address         Unidad de Inmunologia Hospital Universitario La 
Address         Paz, 28046 Madrid, Spain
Telephone       +34-91-7277238/91-7277095
Fax             +34-91-7277095
Email           mcruzgarcia@hulp.insalud.es
Method          Direct sequencing; SSCP
Frequency       on request
Turnaround      1 month
Samples         4 / year
Price           300 EUR/patient,150 EUR/carrier
Comment         Patient samples are only accepted for analysis after prior
Comment         consultation and submission of clinical and laboratory 
Comment         data. Fresh blood wanted or purified DNA from EDTA blood.
//
Disease         Wiskott-Aldrich syndrome and X-linked thrombocytopenia
Accession       I0060
Date            14-Nov-2001 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF71.xml
OMIM            300392
Gene            WAS
IDbase          WASbase
Contact         Prof. Yu-lung Lau/Mr. Chan Koon Wing
Address         Department of Paediatrics and Adolescent of Medicine, The 
Address         University of Hong Kong, L7-55, Laboratory Block, Faculty 
Address         of Medicine Bldg, 21 Sassoon Road, Pokfulam,         
Address         Hong Kong
Telephone       (852)28199362
Fax             (852)28198142
Email           paedlab@hkucc.hku.hk
Method          Direct sequencing
Frequency       4 times/year
Turnaround      3-6 weeks
Samples         16 samples/year
Price           500 USD
//
Disease         X-linked agammaglobulinemia (XLA)
Accession       I0061
Date            29-Jan-2002 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF22.xml
OMIM            300300
Gene            BTK
IDbase          BTKbase
Contact         Prof. Yu-lung Lau/Miss Susanna Fok
Address         Department of Paediatrics and Adolescent of Medicine, The 
Address         University of Hong Kong, L7-55, Laboratory Block, Faculty 
Address         of Medicine Bldg, 21 Sassoon Road, Pokfulam,         
Address         Hong Kong
Telephone       (852)28199362
Fax             (852)28198142
Email           paedlab@hkucc.hku.hk
Method          Direct sequencing
Frequency       4 times/year
Turnaround      3-6 weeks
Samples         16 samples/years
Price           500 USD
//
Disease         X-linked lymphoproliferative syndrome(Duncan disease)
Accession       I0062
Date            28-Feb-2002 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF73.xml
OMIM            308240
Gene            SH2D1A
IDbase          SH2D1Abase
Contact         Prof. Yu-lung Lau/Mr. Chan Koon Wing
Address         Department of Paediatrics and Adolescent of Medicine, The 
Address         University of Hong Kong, L7-55, Laboratory Block, Faculty 
Address         of Medicine Bldg, 21 Sassoon Road, Pokfulam,         
Address         Hong Kong
Telephone       (852)28199362
Fax             (852)28198142
Email           paedlab@hkucc.hku.hk
Method          Direct sequencing
Frequency       4 times/year
Turnaround      3-6 weeks
Samples         16 samples/year
Price           250 USD
//
Disease         RAG1 deficiency
Accession       I0063
Date            10-Jun-2002 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF2.xml
OMIM            179615
Gene            RAG1
IDbase          RAG1base
Contact         Dr. Ma.Cruz Garcia Rodriguez
Address         Unidad de Inmunologia, Hospital Universitario la Paz, 
Address         28046 Madrid, Spain
Telephone       +34-91 7277095/91 7277238
Fax             +34-91 7277095
Email           mcruzgarcia@hulp.insalud.es
Method          Direct sequencing; SSCP
Frequency       on request
Turnaround      1 month
Samples         4/year
Price           400 EUR
Comment         Patient samples are only accepted for analysis after 
Comment         prior consultation and submission of clinical and 
Comment         laboratory data. Fresh blood wanted or purified DNA from 
Comment         EDTA blood
//
Disease         RAG2 deficiency
Accession       I0064
Date            10-Jun-2002 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF3.xml
OMIM            179616
Gene            RAG2
IDbase          RAG2base
Contact         Dr. Ma.Cruz Garcia Rodriguez
Address         Unidad de Inmunologia, Hospital Universitario La Paz, 
Address         28046 Madrid, Spain
Telephone       +34-91 7277095/91 7277238
Fax             +34-91 7277095
Email           mcruzgarcia@hulp.insalud.es
Method          Direct sequencing; SSCP
Frequency       on request
Turnaround      1 month
Samples         4/year
Price           400 EUR
Comment         Patient samples are only accepted for analysis after 
Comment         prior consultation and submission of clinical and 
Comment         laboratory data. Fresh blood wanted or purified DNA from 
Comment         EDTA blood
//
Disease         CVID, ICOS-deficiency
Accession       I0065
Date            23-Oct-2002 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF116.xml
OMIM            240500
Gene            ICOS
IDbase          ICOSbase
Contact         Dr. B. Grimbacher
Address         Medical University of Freiburg, Hugstetter Str. 55, 
Address         79106 Freiburg,  Germany
Telephone       +49-761-270-3401 
Fax             +49-761-270-3531
Email           bgrimbac@medsch.ucl.ac.uk  
Method          Direct sequencing
Frequency       weekly
Turnaround      4 weeks
Samples         Approx. 160
Price           250 Euro
Comment         EDTA blood (50 EUR extra charge)or genomic DNA requested.
//

Disease         X-linked agammaglobulinemia (XLA)
Accession       I0066
Date            05-Dec-2002 (Rel. 1, Created)
Date            19-Sep-2007 (Last updated)
IDR fact file   FF22.xml
OMIM            300300
Gene            BTK
IDbase          BTKbase
Contact         Dr. Lotta Asplund
Address         Clinical Research Center at Novum, level 5,lab 514, 
Address         Karolinska Institute, Halsovagen 7, SE- 14157 Huddinge, 
Address         Sweden
Telephone       +46-8-58583654, +46-8-58583657
Fax             +46-8-58583650
Email           Lotta.Asplund@ki.se
Method          Direct sequencing
Frequency       Upon receipt; Turnaround: aim is 6 weeks
Samples         25/year
Price           450 EUR/patient, 175 Eur/putative carrier
Comment         More than 300 patient samples analysed for BTK mutations 
Comment         to date
//
Disease         RAG1 deficiency
Accession       I0067
Date            05-Dec-2002 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF2.xml
OMIM            179615
Gene            RAG1
IDbase          RAG1base
Contact         Dr. Jean-Pierre de Villartay 
Address         INSERM U429 Hopital Necker, 149 rue de Sevres 
Address         75015 Paris, France
Telephone       +33-1-44495081
Fax             +33-1-42730640 
Email           devillar@necker.fr
Method          Direct sequencing; µsat in consaguineous families
//
Disease         RAG2 deficiency
Accession       I0068
Date            05-Dec-2002 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF3.xml
OMIM            179616
Gene            RAG2
IDbase          RAG2base
Contact         Dr. Jean-Pierre de Villartay 
Address         INSERM U429 Hopital Necker,
Address         149 rue de Sevres 75015 Paris, France
Telephone       +33-1-44495081
Fax             +33-1-42730640 
Email           devillar@necker.fr
Method          Direct sequencing; µsat in consaguineous families
//
Disease         Artemis deficiency
Accession       I0069
Date            05-Dec-2002 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF5.xml
OMIM            605988
Gene            DCLRE1C
IDbase          DCLRE1Cbase
Contact         Dr. Jean-Pierre de Villartay 
Address         INSERM U429 Hopital Necker, 
Address         149 rue de Sevres 75015 Paris, France
Telephone       +33-1-44495081
Fax             +33-1-42730640 
Email           devillar@necker.fr
Method          Direct sequencing; µsat in consaguineous families
//
Disease         Familial hemophagocytic lymphohistiocytosis type 2
Accession       I0070
Date            10-Dec-2002 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF105.xml
OMIM            603552
Gene            PRF1
IDbase          PRF1base
Contact         Dr. de Saint Basile
Address         Hopital Necker Enfants Malades, 149 rue de Sevres, 75015 
Address         Paris, France
Telephone       +33-1-44495080
Fax             +33-1-42730640
Email           sbasile@necker.fr
Method          Direct sequencing; protein expression
Price           305 EUR
Comment         An appointment must be fix prior to sample sending
//
Disease         Griscelli syndrome
Accession       I0071
Date            10-Dec-2002 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF80.xml
OMIM            214450
Gene            MYO5A
IDbase          MYO5Abase
Contact         Dr. de Saint Basile 
Address         Hopital Necker Enfants Malades, 149 rue de Sevres, 
Address         75015 Paris, France
Telephone       +33-1-44495080
Fax             +33-1-42730640
Email           sbasile@necker.fr
Method          Direct sequencing; Hair shaft microscopic analysis
Price           305 EUR
Comment         An appointment must be fix prior to sample sending
//
Disease         X-linked chronic granulomatous disease 
Accession       I0072
Date            14-Jan-2003 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF38.xml
OMIM            306400
Gene            CYBB
IDbase          CYBBbase
Contact         Prof. Yu-lung Lau/Miss Priscilla Mak
Address         Department of Paediatrics and Adolescent Medicine, The 
Address         University of Hong Kong, L7-55, Laboratory Block, Faculty 
Address         of Medicine Bldg, 21 Sassoon Road, Pokfulam, 
Address         Hong Kong 
Telephone       (852)28199362
Fax             (852)28198142
Email           paedlab@hkucc.hku.hk 
Method          Direct sequencing
Frequency       4 times/year 
Turnaround      3-6 weeks 
Samples         16 samples/years 
Price           500 USD 
//
Disease         Cytidine Deaminase (AID) deficiency
Accession       I0073
Date            27-Feb-2003 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF17.xml
OMIM            605257
Gene            AICDA
IDbase          AICDAbase
Contact         Dr. Ma. Cruz Garcia Rodriguez
Address         Unidad de Inmunologia, Hospital la Paz, Paseo de la 
Address         Castellana 261, 28046 Madrid, Spain
Telephone       +34-91-7277238
Fax             +34-91-7277095
Email           mcruzgarcia.hulp@salud.madrid.org
Method          Direct sequencing
Frequency       3 times /year
Turnaround      5-6 weeks
Samples         6 samples /year
Price           300 EUR
//
Disease         SCID with Interleukin 7 receptor alfa deficiency
Accession       I0074
Date            26-Feb-2003 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF106.xml
OMIM            146661
Gene            IL7R
IDbase          IL7Rbase
Contact         Dr. Ma. Cruz Garcia Rodriguez
Address         Unidad de Inmunologia, Hospital Universitario la 
Address         Paz, Paseo de la Castellana 261, 28046 Madrid, Spain
Telephone       +34-91-7277238
Fax             +34-91-7277095
Email           mcruzgarcia.hulp@salud.madrid.org
Method          Direct sequencing
Frequency       4 times / year
Turnaround      5-6 weeks
Samples         4 samples / year
Price           400 EUR
//
Disease         X-linked severe combined immunodeficiency
Accession       I0075
Date            27-Feb-2003 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated) 
IDR factfile    FF8.xml
OMIM            300400
Gene            IL2RG  
IDbase          IL2Rbase
Contact         Jennifer Puck
Address         NHGRI/NIH, Building 49 Room 4A14, 49 Convent Dr.
Address         Bethesda MD, 20892-4442 USA
Telephone       301-402-2194
Fax             301-402-4929
Email           jpuck@nhgri.nih.gov
Method          Direct sequencing
Frequency       as needed
Turnaround      2-4 weeks
Samples         50 SCID
Price           No charge because work is on research protocol
Comment         Testing is done as part of a research protocol only.
Comment         Eligibility will be determined from screening data that
Comment         must be submitted prior to enrollnment (pedigree and
Comment         clinical, lab data). Also, Dr. Puck's study consent form
Comment         must be signed by subject and submitted with sample. Report
Comment         is sent to referring provider. Dr. Puck's lab is certified
Comment         and licensed under US CLIA. (Clinical Laboratory Comment  
    Comment         Improvement Act).
//
Disease         Autoimmune lymphoproliferative syndrome (ALPS)
Accession       I0076
Date            27-Feb-2003 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR factfile    FF36.xml
OMIM            601859
Gene            TNFRSF6
IDbase          TNFRSF6base
Contact         Jennifer Puck
Address         NHGRI/NIH, Building 49 Room 4A14, 49 Convent Dr.,
Address         Bethesda MD, 20892-4442 USA
Telephone       301-402-2194
Fax             301-402-4929
Email           jpuck@nhgri.nih.gov
Method          Direct sequencing
Frequency       as needed
Turnaround      2-4 weeks
Samples         60 ALPS
Price           No charge because work is on research protocol.
Comment         Testing is done as part of a research protocol only.
Comment         Eligibility will be determined from screening data that
Comment         must be submitted prior to enrollnment (pedigree and
Comment         clinical, lab data). Also, Dr. Puck's study consent form
Comment         must be signed by subject and submitted with sample. Report
Comment         is sent to referring provider. Dr. Puck's lab is certified
Comment         and licensed under US CLIA (Clinical Laboratory Improvement
Comment         Act).
//
Disease         Leukocyte adhesion deficiency 1
Accession       I0077
Date            14-Feb-2003 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF8.xml
OMIM            600065 
Gene            ITGB2
IDbase          ITGB2base
Contact         Prof. Yu-lung Lau/Mr.Chan Koon Wing
Address         Department of Paediatrics and Adolescent Medicine, The 
Address         University of Hong Kong, L7-55, Laboratory Block, Faculty 
Address         of Medicine Bldg, 21 Sassoon Road, Pokfulam,
Address         Hong Kong  
Telephone       (852)28199362
Fax             (852)28198142
Email           paedlab@hkucc.hku.hk 
Method          Direct sequencing
Frequency       4 times/year 
Turnaround      3-6 weeks 
Samples         16 samples/years 
Price           500 USD
// 
Disease         X-linked hyper-IgM syndrome (CD40L deficiency)
Accession       I0078
Date            29-May-2003 (Rel. 1, Created)
Date            16-Mar-2006 (Last updated)
IDR fact file   FF16.xml
OMIM            308230 
Gene            TNFSF5
IDbase          TNFSF5base
Contact         Richard Wenstrup, MD
Address         Cytogenetics and Molecular Genetics Laboratory, 3333 Burnet
Address         Ave. NRB 1005, Cincinnati, OH 45229,USA
Telephone       513-636-4474
Fax             513-636-4373
Email           moleculargenetics@cchmc.org
URL             www.cincinnatichildrens.org/molecular-genetics/
Method          Direct sequencing
Frequency       as needed
Turnaround      1 month
Price           call for price
Comment         Sequencing of entire coding region of CD40 ligand gene.
Comment         Indications: Confirmation of diagnosis, carrier testing 
Comment         and prenatal diagnosis (with prior arrangement only).
//
Disease         X-linked SCID(gammac-chain deficiency)
Accession       I0079
Date            29-May-2003 (Rel. 1, Created)
Date            16-Mar-2006 (Last updated)
IDR fact file   FF8.xml
OMIM            300400
Gene            IL2RG
IDbase          IL2RGbase
Contact         Richard Wenstrup, MD
Address         Cytogenetics and Molecular Genetics Laboratory, 3333 Burnet
Address         Ave. NRB 1005, Cincinnati, OH 45229,USA
Telephone       513-636-4474
Fax             513-636-4373
Email           moleculargenetics@cchmc.org
URL             www.cincinnatichildrens.org/molecular-genetics/
Method          Direct sequencing
Frequency       as needed
Turnaround      1 month
Price           call for price
Comment         Sequencing of entire coding region of IL2RG.
Comment         Indications:  Confirmation of diagnosis, carrier 
Comment         detection, and prenatal diagnosis (by prior arrangement 
Comment         only).
//
Disease         X-linked lymphoproliferative syndrome(Duncan disease) 
Accession       I0080
Date            29-May-2003 (Rel. 1, Created)
Date            16-Mar-2006 (Last updated)
IDR fact file   FF73.xml
OMIM            308240
Gene            SH2D1A
IDbase          SH2D1Abase
Contact         Richard Wenstrup, MD
Address         Cytogenetics and Molecular Genetics Laboratory, 3333 Burnet
Address         Ave. NRB 1005, Cincinnati, OH 45229,USA
Telephone       513-636-4474
Fax             513-636-4373
Email           moleculargenetics@cchmc.org
URL             www.cincinnatichildrens.org/molecular-genetics/
Method          Direct sequencing
Frequency       as needed
Turnaround      1 month
Comment         Sequencing of the entire coding region of SH2D1A.  
Comment         Indications:  confirmation of diagnosis, carrier
Comment         detection, and prenatal diagnosis (by prior arrangement 
Comment         only).  Sequencing will not detect large deletions found 
Comment         in about 25% of female carriers.
//
Disease         Familial haemophagocytic lymphohistiocytosis type 2
Accession       I0081
Date            29-May-2003 (Rel. 1, Created)
Date            16-Mar-2006 (Last updated)
IDR fact file   FF105.xml
OMIM            170280 
Gene            PRF1
IDbase          PRF1base
Contact         Richard Wenstrup, MD
Address         Cytogenetics and Molecular Genetics Laboratory, 3333 Burnet
Address         Ave. NRB 1005, Cincinnati, OH 45229,USA
Telephone       513-636-4474
Fax             513-636-4373
Email           moleculargenetics@cchmc.org
URL             www.cincinnatichildrens.org/molecular-genetics/
Method          Direct sequencing
Frequency       as needed
Turnaround      1 month
Comment         Sequencing of entire coding region of PRF 1.  Sequencing 
Comment         identifies mutations in about 30% of familial HLH 
Comment         worldwide.  Indications:  Confirmation of diagnosis, 
Comment         carrier testing and prenatal diagnosis (by prior
Comment         arrangement only).
//
Disease         Osteopetrosis
Accession       I0082
Date            12-Aug-2003 (Rel. 1, Created)
Date            20-Oct-2005 (Last updated)
IDR fact file   FF157
OMIM            604592
Gene            TCIRG1
IDbase          TCIRG1base
Contact         PD Dr. Ansgar Schulz
Address         Universitätsklinik fur Kinder und Jugendmdizin,  
Address         Eythstrasse 24, D-89075 Ulm, Germany
Telephone       (+49) 731 500 27747
Fax             (+49) 731 500 26685
Email           ansgar.schulz@uni-ulm.de
Method          Direct sequencing
Frequency       weekly
Turnaround      4 weeks
Samples         20
Price           for free
Comment         CLCN7 and TCIRG1 will be analyzed
//
Disease         Ataxia-telangiectasia
Accession       I0083
Date            05-Apr-2001 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF87.xml
OMIM            208900
Gene            ATM
Contact         Dr. Lennart Hammarstrom
Address         Klinisk Immunology, F79 Huddinge University Hospital,
Address         SE-141 86 Stockholm, Sweden
Telephone       (+46)8 608 9115
Fax             (+46)8 585 81390
Email           Lennart.Hammarstrom@labmed.ki.se
Method          SSCP
Frequency       on demand
Turnaround      20-40 per year 
Samples         not performed on commercial bases
Price           not performed on commercial bases
//
Disease         RAG1 deficiency
Accession       I0084
Date            03-May-2005 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF2.xml
OMIM            179615
Gene            RAG1
IDbase          RAG1base
Contact         Prof. Yu-lung Lau/Mr.Chan Koon Wing
Address         University of Hong Kong, L7-55, Laboratory Block, Faculty
Address         of Medicine Bldg, 21 Sassoon Road, Pokfulam, 
Address         Hong Kong 
Telephone       (852)28199362
Fax             (852)28198142
Email           paedlab@hkucc.hku.hk
Method          Direct sequencing
Frequency       4 times/year
Turnaround      3-6 weeks
Samples         16 samples/years
Price           250 USD
//
Disease         RAG2 deficiency
Accession       I0085
Date            03-May-2005 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF3.xml
OMIM            179616
Gene            RAG2
IDbase          RAG2base
Contact         Prof. Yu-lung Lau/Mr.Chan Koon Wing
Address         University of Hong Kong, L7-55, Laboratory Block, Faculty
Address         of Medicine Bldg, 21 Sassoon Road, Pokfulam, 
Address         Hong Kong 
Telephone       (852)28199362
Fax             (852)28198142
Email           paedlab@hkucc.hku.hk
Method          Direct sequencing
Frequency       4 times/year
Turnaround      3-6 weeks
Samples         16 samples/years
Price           250 USD
//
Disease         X-linked SCID(gammac-chain deficiency)
Accession       I0086
Date            03-May-2005 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF8.xml
OMIM            300400
Gene            IL2RG
IDbase          IL2RGbase
Contact         Prof. Yu-lung Lau/Mr.Chan Koon Wing
Address         University of Hong Kong, L7-55, Laboratory Block, Faculty
Address         of Medicine Bldg, 21 Sassoon Road, Pokfulam, 
Address         Hong Kong 
Telephone       (852)28199362
Fax             (852)28198142
Email           paedlab@hkucc.hku.hk
Method          Direct sequencing
Frequency       4 times/year
Turnaround      3-6 weeks
Samples         16 samples/years
Price           250 USD
//
Disease         X-linked hyper-IgM syndrome (CD40L deficiency)
Accession       I0087
Date            03-May-2005 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF16.xml
OMIM            308230
Gene            TNFSF5
IDbase          TNFSF5base
Contact         Prof. Yu-lung Lau/Miss Susanna Fok
Address         Department of Paediatrics and Adolescent Medicine, The
Address         University of Hong Kong, L7-55, Laboratory Block, Faculty
Address         of Medicine Bldg, 21 Sassoon Road, Pokfulam,
Address         Hong Kong 
Telephone       (852)28199362
Fax             (852)28198142
Email           paedlab@hkucc.hku.hk
Method          Direct sequencing
Frequency       4 times/year
Turnaround      3-6 weeks
Samples         16 samples/years
Price           USD 250
//
Disease         Non-X-linked hyper-IgM syndrome
Accession       I0088
Date            04-Sep-2005 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF17.xml
OMIM            605257
Gene            AICDA
IDbase          AICDAbase
Contact         Dr. Laszlo Marodi
Address         Immunology Laboratory, Dept. of Infectology and Paediatric 
Address         Immunology, Univ. of Debrecen, Hungary 
Telephone       +36 52 416 841
Fax             +36 52 430 323
Email           lmarodi@jaguar.dote.hu
Method          Direct sequencing
Frequency       on demand
Turnaround      4 weeks
Samples         3
Price           see below
Comment         Price is fixed by the insurance company
//
Disease         Wiskott-Aldrich syndrome and X-linked thrombocytopenia
Accession       I0089
Date            04-Sep-2005 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF71.xml
OMIM            300392
Gene            WAS
IDbase          WASbase
Contact         Dr. Laszlo Marodi
Address         Immunology Laboratory, Dept. of Infectology and Paediatric 
Address         Immunology, Univ. of Debrecen, Hungary 
Telephone       +36 52 416 841
Fax             +36 52 430 323
Email           lmarodi@jaguar.dote.hu
Method          Direct sequencing
Frequency       on demand
Turnaround      4 weeks
Samples         5
Price           see below
Comment         Price is fixed by the insurance company
//
Disease         X-linked SCID(gammac-chain deficiency)
Accession       I0090
Date            04-Sep-2005 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF8.xml
OMIM            300400
Gene            IL2RG
IDbase          IL2RGbase
Contact         Dr. Laszlo Marodi
Address         Immunology Laboratory, Dept. of Infectology and Paediatric 
Address         Immunology, Univ. of Debrecen, Hungary 
Telephone       +36 52 416 841
Fax             +36 52 430 323
Email           lmarodi@jaguar.dote.hu
Method          Direct sequencing
Frequency       on demand
Turnaround      4 weeks
Samples         5
Price           see below
Comment         Price is fixed by the insurance company
//
Disease         X-linked hyper-IgM syndrome (CD40L deficiency)
Accession       I0091
Date            04-Sep-2005 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF16.xml
OMIM            308230
Gene            TNFSF5
IDbase          TNFSF5base
Contact         Dr. Laszlo Marodi
Address         Immunology Laboratory, Dept. of Infectology and Paediatric 
Address         Immunology, Univ. of Debrecen, Hungary 
Telephone       +36 52 416 841
Fax             +36 52 430 323
Email           lmarodi@jaguar.dote.hu
Method          Direct sequencing
Frequency       on demand
Turnaround      4 weeks
Samples         5
Price           see below
Comment         Price is fixed by the insurance company
//
Disease         X-linked lymphoproliferative syndrome (Duncan disease)
Accession       I0092
Date            04-Sep-2005 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF73.xml
OMIM            308240
Gene            SH2D1A
IDbase          SH2D1Abase
Contact         Dr. Laszlo Marodi
Address         Immunology Laboratory, Dept. of Infectology and Paediatric 
Address         Immunology, Univ. of Debrecen, Hungary 
Telephone       +36 52 416 841
Fax             +36 52 430 323
Email           lmarodi@jaguar.dote.hu
Method          Direct sequencing
Frequency       on demand
Turnaround      4 weeks
Samples         5
Price           see below
Comment         Price is fixed by the insurance company
//
Disease         Shwachman syndrome
Accession       I0093
Date            04-Sep-2005 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF84.xml
OMIM            260400
Gene            SBDS
IDbase          SBDSbase
Contact         Dr. Laszlo Marodi
Address         Immunology Laboratory, Dept. of Infectology and Paediatric 
Address         Immunology, Univ. of Debrecen, Hungary 
Telephone       +36 52 416 841
Fax             +36 52 430 323
Email           lmarodi@jaguar.dote.hu
Method          Direct sequencing
Frequency       on demand
Turnaround      4 weeks
Samples         5
Price           see below
Comment         Price is fixed by the insurance company
//
Disease         SCID with Interleukin 7 receptor alfa deficiency
Accession       I0094
Date            04-Sep-2005 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF106.xml
OMIM            146661
Gene            IL7R
IDbase          IL7Rbase
Contact         Dr. Laszlo Marodi
Address         Immunology Laboratory, Dept. of Infectology and Paediatric 
Address         Immunology, Univ. of Debrecen, Hungary 
Telephone       +36 52 416 841
Fax             +36 52 430 323
Email           lmarodi@jaguar.dote.hu
Method          Direct sequencing
Frequency       on demand
Turnaround      4 weeks
Samples         5
Price           see below
Comment         Price is fixed by the insurance company
//
Disease         APECED
Accession       I0095
Date            04-Sep-2005 (Rel. 1, Created)
Date            07-Sep-2005 (Last updated)
IDR fact file   FF72.xml
OMIM            607358
Gene            AIRE
IDbase          AIREbase
Contact         Dr. Laszlo Marodi
Address         Immunology Laboratory, Dept. of Infectology and Paediatric 
Address         Immunology, Univ. of Debrecen, Hungary 
Telephone       +36 52 416 841
Fax             +36 52 430 323
Email           lmarodi@jaguar.dote.hu
Method          Direct sequencing
Frequency       on demand
Turnaround      4 weeks
Samples         5
Price           see below
Comment         Price is fixed by the insurance company
//
Disease         SCID with Interleukin 7 receptor alfa deficiency
Accession       I0096
Date            15-Dec-2005 (Rel. 1, Created)
Date            15-Dec-2005 (Last updated)
IDR fact file   FF106.xml
OMIM            146661
Gene            IL7R
IDbase          IL7Rbase
Contact         Prof. Dr. G. Lahr
Address         Klinik für Kinder- und Jugendmedizin, Universität Ulm,
Address         Eythstr. 24, D-89075 Ulm, Germany
Telephone       (+49) 731 500 27788
Fax             (+49) 731 500 26685
Email           ansgar.schulz@uni-ulm.de
Method          Direct sequencing
Turnaround      4 weeks
Price           for free
Comment         In B+ SCID patients IL2RG, IL7R and JAK3 will be analyzed
Comment         subsequently
//
Disease         JAK3 deficiency
Accession       I0097
Date            15-Dec-2005 (Rel. 1, Created)
Date            15-Dec-2005 (Last updated)
IDR fact file   FF9.xml
OMIM            600173
Gene            JAK3
IDbase          JAK3base
Contact         Prof. Dr. G. Lahr
Address         Klinik für Kinder- und Jugendmedizin, Universität Ulm
Address         Eythstr. 24,D-89075, Ulm, Germany
Telephone       (+49) 731 500 27788
Fax             (+49) 731 500 26685
Email           ansgar.schulz@uni-ulm.de
Method          Direct sequencing
Turnaround      4 weeks
Price           for free
Comment         In B+ SCID patients IL2RG, Il7R and JAK3 can be analyzed
//
Disease         IL-2 receptor α-chain deficiency
Accession       I0098
Date            15-Dec-2005 (Rel. 1, Created)
Date            15-Dec-2005 (Last updated)
IDR fact file   FF63.xml
OMIM            147730
Gene            IL2RA
IDbase          IL2RAbase
Contact         Prof. Dr. G. Lahr
Address         Klinik für Kinder- und Jugendmedizin, Universität Ulm
Address         Eythstr. 24, D-89075 Ulm, Germany
Telephone       (+49) 731 500 27788
Fax             (+49) 731 500 26685
Email           ansgar.schulz@uni-ulm.de
Method          Direct sequencing
Turnaround      2 weeks
Samples         15
Price           for free
Comment         In B+ SCID patients IL2RG, IL7R and JAK3 can be analyzed
//
Disease         ZAP-70 deficiency
Accession       I0099
Date            15-Dec-2005 (Rel. 1, Created)
Date            15-Dec-2005 (Last updated)
IDR fact file   FF62.xml
OMIM            176947
Gene            ZAP70
IDbase          ZAP70base
Contact         Prof. Dr. G. Lahr
Address         Klinik für Kinder- und Jugendmedizin, Universität Ulm
Address         Eythstr. 24, D-89075 Ulm, Germany
Telephone       (+49) 731 500 27788
Fax             (+49) 731 500 26685
Email           ansgar.schulz@uni-ulm.de
Method          Direct sequencing
Turnaround      4 weeks
Price           for free
//
Disease         X-linked hyper-IgM syndrome (CD40L deficiency)
Accession       I0100
Date            15-Dec-2005 (Rel. 1, Created)
Date            15-Dec-2005 (Last updated)
IDR fact file   FF16.xml
OMIM            300386
Gene            TNFSF5
IDbase          CD40Lbase
Contact         Prof. Dr. G. Lahr
Address         Klinik für Kinder- und Jugendmedizin, Universität Ulm 
Address         Eythstr. 24, D-89075 Ulm, Germany
Telephone       (+49) 731 500 27788
Fax             (+49) 731 500 26685
Email           ansgar.schulz@uni-ulm.de
Method          Direct sequencing
Turnaround      4 weeks
Price           for free
//
Disease         Familial haemophagocytic lymphohistiocytosis type 2
Accession       I0101
Date            15-Dec-2005 (Rel. 1, Created)
Date            15-Dec-2005 (Last updated)
IDR fact file   FF105.xml
OMIM            170280
Gene            PRF1
IDbase          PRF1base
Contact         Prof. Dr. G. Lahr
Address         Klinik für Kinder- und Jugendmedizin, Universität Ulm
Address         Eythstr. 24, D-89075 Ulm, Germany
Telephone       (+49) 731 500 27788
Fax             (+49) 731 500 26685
Email           ansgar.schulz@uni-ulm.de
Method          Direct sequencing
Turnaround      4 weeks
Price           for free
//
Disease         IFNgamma-receptor 1 deficiency
Accession       I0102
Date            15-Dec-2005 (Rel. 1, Created)
Date            15-Dec-2005 (Last updated)
IDR fact file   FF44.xml
OMIM            107470
Gene            IFNGR1
IDbase          IFNGR1base           
Contact         Prof. Dr. G. Lahr
Address         Klinik für Kinder- und Jugendmedizin, Universität Ulm
Address         Eythstr. 24, D-89075 Ulm, Germany
Telephone       (+49) 731 500 27788
Fax             (+49) 731 500 26685
Email           ansgar.schulz@uni-ulm.de
Method          Direct sequencing
Turnaround      4 weeks
Price           for free
//
Disease         Immunodeficiency, polyendocrinopathy, enteropathy, X-linked
Accession       I0103
Date            15-Dec-2005 (Rel. 1, Created)
Date            15-Dec-2005 (Last updated)
IDR fact file   FF78.xml
OMIM            300292
Gene            FOXP3
IDbase          FOXP3base
Contact         Prof. Dr. G. Lahr
Address         Klinik für Kinder- und Jugendmedizin, Universität Ulm
Address         Eythstr. 24, D-89075 Ulm, Germany
Telephone       (+49) 731 500 27788
Fax             (+49) 731 500 26685
Email           ansgar.schulz@uni-ulm.de
Method          Direct sequencing
Turnaround      4 weeks
Price           for free
//
Disease         WHIM (Warts, Hypogammaglobulinemia, Infections and
Disease         Myelokathexis)
Accession       I0104
Date            09-Mar-2006 (Rel. 1, Created)
Date            09-Mar-2006 (Last updated)
IDR fact file   FF7.xml
OMIM            193670
Gene            CXCR4
IDbase          CXCR4base
Contact         Dr. Lotta Asplund
Address         Clinical Research Center at Novum, level 5,lab 514, 
Address         Karolinska Institute, Halsovagen 7, SE- 14157 Huddinge, 
Address         Sweden
Telephone       +46-8-58583654, +46-8-58583657
Fax             +46-8-58583650
Email           Lotta.Asplund@ki.se
Method          Direct sequencing
Frequency       Samples are normally completed within one month
Samples         Statistics not yet available
Price           200 EUR/patient, 150 Eur/family member        
//
Disease         Wiskott-Aldrich syndrome and X-linked thrombocytopenia
Accession       I0105
Date            05-Apr-2006 (Rel. 1, Created)
Date            05-Apr-2006 (Last updated)
IDR fact file   FF71.xml
OMIM            300392
Gene            WAS
IDbase          WASbase
Contact         Richard Wenstrup, MD
Address         Cytogenetics and Molecular Genetics Laboratory, 3333
Address         Burnet Ave. NRB 1005, Cincinnati, OH 45229 USA
Telephone       513-636-4474
Fax             513-636-4373
Email           moleculargenetics@cchmc.org
URL             www.cincinnatichildrens.org/molecular-genetics
Method          Direct sequencing
Frequency       as needed
Turnaround      3-4 weeks
Samples         200
Price           call for price
Comment         Sequencing of entire coding region and exon/intron
Comment         boundaries of WAS gene.  Indications:  confirmation of
Comment         diagnosis, carrier testing and prenatal diagnosis (by prior
Comment         arrangement only).
//
Disease         Familial hemophagocytic lymphohistiocytosis 3
Accession       I0106
Date            05-Apr-2006 (Rel. 1, Created)
Date            05-Apr-2006 (Last updated)
IDR fact file   FF126.xml
OMIM            608897
Gene            UNC13D
IDbase          UNC13Dbase
Contact         Richard Wenstrup, MD
Address         Cytogenetics and Molecular Genetics Laboratory, 3333
Address         Burnet Ave. NRB 1005, Cincinnati, OH 45229 USA
Telephone       513-636-4474
Fax             513-636-4373
Email           moleculargenetics@cchmc.org
URL             www.cincinnatichildrens.org/molecular-genetics
Method          Direct sequencing
Frequency       as needed
Turnaround      4-8 weeks
Samples         200
Price           call for price
Comment         Sequencing of entire coding region of Munc13-4 gene.
Comment         Indications:  confirmation of diagnosis, carrier testing
Comment         and prenatal diagnosis (by prior arrangement only).
//
Disease         ALPS type Ia (defective CD95)
Accession       I0107
Date            05-Apr-2006 (Rel. 1, Created)
Date            05-Apr-2006 (Last updated)
IDR fact file   FF36.xml
OMIM            601859
Gene            TNFRSF6
IDbase          TNFRSF6base  
Contact         Richard Wenstrup, MD
Address         Cytogenetics and Molecular Genetics Laboratory, 3333
Address         Burnet Ave. NRB 1005, Cincinnati, OH 45229 USA
Telephone       513-636-4474
Fax             513-636-4373
Email           moleculargenetics@cchmc.org
URL             www.cincinnatichildrens.org/molecular-genetics
Method          Direct sequencing
Turnaround      4 weeks
Samples         50
Price           call for price
Comment         Sequencing of entire coding region and exon/intron
Comment         boundaries of FAS gene.  Indications:  confirmation of
Comment         diagnosis, carrier testing for medical management, prenatal
Comment         diagnosis (by prior arrangement only).
//
Disease         Non-X-linked hyper-IgM syndrome
Accession       I0108
Date            06-Jun-2006 (Rel. 1, Created)
Date            06-Jun-2006 (Last updated)
IDR fact file   FF17.xml
OMIM            605257
Gene            AICDA
IDbase          AICDAbase
Contact         Prof. Yu-lung Lau/Mr. Koon-Wing Chan
Address         Department of Paediatrics and Adolescent Medicine, The
Address         University of Hong Kong, L7-55, Laboratory Block, Faculty
Address         of Medicine Bldg, 21 Sassoon Road, Pokfulam, Hong
Address         Kong 
Telephone       (852)28199362
Fax             (852)28198142
Email           paedlab@hkucc.hku.hk
URL             http://www.hku.hk/paed/
Method          Direct sequencing
Turnaround      3-6 weeks
Price           250 USD
//
Disease         Immunodeficiency, polyendocrinopathy, enteropathy, X-linked
Accession       I0109
Date            06-Jun-2006 (Rel. 1, Created)
Date            06-Jun-2006 (Last updated)
IDR fact file   FF78.xml
OMIM            300292
Gene            FOXP3
IDbase          FOXP3base
Contact         Prof. Yu-lung Lau/Mr. Koon-Wing Chan
Address         Department of Paediatrics and Adolescent Medicine, The
Address         University of Hong Kong, L7-55, Laboratory Block, Faculty
Address         of Medicine Bldg, 21 Sassoon Road, Pokfulam, Hong
Address         Kong 
Telephone       (852)28199362
Fax             (852)28198142
Email           paedlab@hkucc.hku.hk
URL             http://www.hku.hk/paed/
Method          Direct sequencing
Turnaround      3-6 weeks
Price           500 USD
//
Disease         Interleukin-12 (IL-12) p40 deficiency
Accession       I0110
Date            06-Jun-2006 (Rel. 1, Created)
Date            06-Jun-2006 (Last updated)
IDR fact file   FF46.xml
OMIM            161561
Gene            IL12B
IDbase          IL12Bbase
Contact         Prof. Yu-lung Lau/Mr. Koon-Wing Chan
Address         Department of Paediatrics and Adolescent Medicine, The
Address         University of Hong Kong, L7-55, Laboratory Block, Faculty
Address         of Medicine Bldg, 21 Sassoon Road, Pokfulam, Hong
Address         Kong 
Telephone       (852)28199362
Fax             (852)28198142
Email           paedlab@hkucc.hku.hk
URL             http://www.hku.hk/paed/
Method          Direct sequencing
Turnaround      3-6 weeks
Price           250 USD
//
Disease         Interleukin-12 receptor beta1 deficiency
Accession       I0111
Date            06-Jun-2006 (Rel. 1, Created)
Date            06-Jun-2006 (Last updated)
IDR fact file   FF47.xml
OMIM            601604
Gene            IL12RB1
IDbase          IL12RB1base
Contact         Prof. Yu-lung Lau/Mr. Koon-Wing Chan
Address         Department of Paediatrics and Adolescent Medicine, The
Address         University of Hong Kong, L7-55, Laboratory Block, Faculty
Address         of Medicine Bldg, 21 Sassoon Road, Pokfulam, Hong
Address         Kong 
Telephone       (852)28199362
Fax             (852)28198142
Email           paedlab@hkucc.hku.hk
URL             http://www.hku.hk/paed/
Method          Direct sequencing
Turnaround      3-6 weeks
Price           500 USD
//
Disease         IFNgamma-receptor 1 deficiency
Accession       I0112
Date            06-Jun-2006 (Rel. 1, Created)
Date            06-Jun-2006 (Last updated)
IDR fact file   FF44.xml
OMIM            107470
Gene            IFNGR1
IDbase          IFNGR1base
Contact         Prof. Yu-lung Lau/Mr. Koon-Wing Chan
Address         Department of Paediatrics and Adolescent Medicine, The
Address         University of Hong Kong, L7-55, Laboratory Block, Faculty
Address         of Medicine Bldg, 21 Sassoon Road, Pokfulam, Hong
Address         Kong 
Telephone       (852)28199362
Fax             (852)28198142
Email           paedlab@hkucc.hku.hk
URL             http://www.hku.hk/paed/
Method          Direct sequencing
Turnaround      3-6 weeks
Price           250 USD
//
Disease         Mannose-binding lectin (protein) deficiency
Accession       I0113
Date            31-Aug-2006 (Rel. 1, Created)
Date            31-Aug-2006 (Last updated)
IDR fact file   FF96.xml
OMIM            154545
Gene            MBL2
Contact         Prof. Dirk Roos
Address         Sanquin Research, Plemanlaan 125, 1066CX Amsterdam,
Address         Netherlands
Telephone       31-20-5123377
Fax             31-20-5123474
Email           d.roos@sanquin.nl
Method          Direct sequencing
Frequency       10 times per year
Turnaround      about 4 weeks
Samples         200 per year
Price           550 Euro
Comment         Only after consultation by email. Needed: purified DNA from
Comment         EDTA blood or from citrate blood, NOT from heparin blood.
Comment         ELISA to establish MBL deficiency.
//
Disease         Glucose 6-phosphate dehydrogenase deficiency
Accession       I0114
Date            31-Aug-2006 (Rel. 1, Created)
Date            31-Aug-2006 (Last updated)
IDR fact file   FF81.xml
OMIM            305900
Gene            G6PD
Contact         Prof. Dirk Roos
Address         Sanquin Research, Plemanlaan 125, 1066CX Amsterdam,
Address         Netherlands
Telephone       31-20-5123377
Fax             31-20-5123474
Email           d.roos@sanquin.nl
Method          Direct sequencing
Frequency       on request
Turnaround      about 2 months
Samples         1-2 per year
Price           550 Euro
Comment         Only after consultation by email. Needed: purified DNA from
Comment         EDTA blood or from citrate blood, NOT from heparin blood.
Comment         G6PD enzyme assay in leukocytes to establish G6PD
Comment         deficiency in leukocytes.
//
Disease         C4A deficiency
Accession       I0115
Date            31-Aug-2006 (Rel. 1, Created)
Date            31-Aug-2006 (Last updated)
IDR fact file   FF53.xml
OMIM            120810
Gene            C4A
Contact         Prof. Dirk Roos
Address         Sanquin Research, Plemanlaan 125, 1066CX Amsterdam,
Address         Netherlands
Telephone       31-20-5123377
Fax             31-20-5123474
Email           d.roos@sanquin.nl
Method          Other; MLPA
Frequency       on request
Turnaround      about 1 month
Samples         10-20 per year
Price           550 Euro
Comment         Only after consultation by email. Needed: purified DNA from
Comment         EDTA blood or from citrate blood, NOT from heparin blood.
//
Disease         C4B deficiency
Accession       I0116
Date            31-Aug-2006 (Rel. 1, Created)
Date            31-Aug-2006 (Last updated)
IDR fact file   FF54.xml
OMIM            120820
Gene            C4B
Contact         Prof. Dirk Roos
Address         Sanquin Research, Plemanlaan 125, 1066CX Amsterdam,
Address         Netherlands
Telephone       31-20-5123377
Fax             31-20-5123474
Email           d.roos@sanquin.nl
Method          Other; MLPA
Frequency       on request
Turnaround      about 1 month
Samples         10-20 per year
Price           550 Euro
Comment         Only after consultation by email. Needed: purified DNA from
Comment         EDTA blood or from citrate blood, NOT from heparin blood.
//
Disease         Factor D deficiency
Accession       I0117
Date            31-Aug-2006 (Rel. 1, Created)
Date            31-Aug-2006 (Last updated)
IDR fact file   FF98.xml
OMIM            134350
Gene            DF
Contact         Prof. Dirk Roos
Address         Sanquin Research, Plemanlaan 125, 1066CX Amsterdam,
Address         Netherlands
Telephone       31-20-5123377
Fax             31-20-5123474
Email           d.roos@sanquin.nl
Method          Direct sequencing
Frequency       on request
Turnaround      about 1 month
Samples         1-2 per year
Price           550 Euro
Comment         Only after consultation by email. Needed: purified DNA from
Comment         EDTA blood or from citrate blood, NOT from heparin blood.
Comment         AP50 test to establish deficiency in alternative pathway of
Comment         complement activation.
//
Disease         Myeloperoxidase deficiency
Accession       I0118
Date            31-Aug-2006 (Rel. 1, Created)
Date            31-Aug-2006 (Last updated)
IDR fact file   FF82.xml
OMIM            606989
Gene            MPO
IDbase          MPObase
Contact         Prof. Dirk Roos
Address         Sanquin Research, Plemanlaan 125, 1066CX Amsterdam,
Address         Netherlands
Telephone       31-20-5123377
Fax             31-20-5123474
Email           d.roos@sanquin.nl
Method          Direct sequencing
Frequency       on request
Turnaround      about 1 month
Samples         1-2 per year
Price           550 Euro
Comment         Only after consultation by email. Needed: purified DNA from
Comment         EDTA blood or from citrate blood, NOT from heparin blood.
Comment         Enzymatic analysis to establish MPO deficiency.
//
Disease         p14 deficiency
Accession       I0119
Date            10-Oct-2007 (Rel. 1, Created)
Date            10-Oct-2007 (Last updated)
IDR fact file   FF161.xml
OMIM            610798
Gene            MAPBPIP
IDbase          MAPBPIPbase
Contact         Christoph Klein, MD PhD
Address         Associate Professor of Pediatric Hematology / 
Address         Oncology Hannover Medical School
Address         Department of Pediatric Hematology, Oncology
Address         Experimental Hematology / Oncology, OE
Address         6780 Carl-Neuberg-Str. 1 30625 Hannover, Germany
Telephone       +49-511-532-6711
Fax             +49-511-532-9120
Email           klein.christoph@mh-hannover.de
URL             http://www99.mh-hannover.de/ 
URL             kliniken/paed_haemonko/kleinlab/KleinLab/Home.html
Method          Direct sequencing
Frequency       as requested
Turnaround      about 1 week
Samples         10
Price           100 Euros
Comment         p14 deficiency is an novel primary immunodeficiency
Comment         syndrome associating congenital neutopenia,
Comment         hypopigmentation of skin and hair, B and T cell deficiency
Comment         and low growth. It is caused by deficiency of the endosomal
Comment         adaptor protein p14 and resembles diseases such as
Comment         Hemansky-Pudlak syndrome type 2, Griscelli syndrome type 2,
Comment         or Chediak-Higashi syndrome. In case you suspect p14
Comment         deficiency in your patients please contact us to decide
Comment         upon the best material for analysis. In general 2-5 ml of
Comment         blood are sufficient, but other sample types may be also
Comment         suitable.
//

Disease         RAG1 deficiency
Accession       I0128
Date            16-Jan-2008 (Rel. 1, Created)
Date            16-Jan-2008 (Last updated)
IDR fact file   FF2.xml
OMIM            179615
Gene            RAG1
IDbase          RAG1base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         RAG2 deficiency
Accession       I0129
Date            16-Jan-2008 (Rel. 1, Created)
Date            16-Jan-2008 (Last updated)
IDR fact file   FF3.xml
OMIM            179616
Gene            RAG2
IDbase          RAG2base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599   
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Artemis deficiency
Accession       I0130
Date            16-Jan-2008 (Rel. 1, Created)
Date            16-Jan-2008 (Last updated)
IDR fact file   FF5.xml
OMIM            605988
Gene            DCLRE1C
IDbase          DCLRE1Cbase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         JAK3 deficiency
Accession       I0131
Date            17-Jan-2008 (Rel. 1, Created)
Date            17-Jan-2008 (Last updated)
IDR fact file   FF9.xml
OMIM            600173
Gene            JAK3
IDbase          JAK3base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         IL7 receptor alpha chain deficiency
Accession       I0132
Date            17-Jan-2008 (Rel. 1, Created)
Date            17-Jan-2008 (Last updated)
IDR fact file   FF106.xml
OMIM            146661
Gene            IL7R
IDbase          IL7Rbase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         CD45 deficiency
Accession       I0133
IDR fact file   FF6.xml
OMIM            151460
Gene            PTPRC
IDbase          PTPRCbase
Date            17-Jan-2008 (Rel. 1, Created)
Date            17-Jan-2008 (Last updated)
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         CD3delta deficiency
Accession       I0134
Date            17-Jan-2008 (Rel. 1, Created)
Date            17-Jan-2008 (Last updated)
IDR fact file   FF111.xml
OMIM            186790
Gene            CD3D
IDbase          CD3Dbase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         CD3epsilon deficiency
Accession       I0135
Date            17-Jan-2008 (Rel. 1, Created)
Date            17-Jan-2008 (Last updated)
IDR fact file   FF20.xml
OMIM            186830
Gene            CD3E
IDbase          CD3Ebase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         CD3zeta deficiency
Accession       I0136
Date            17-Jan-2008 (Rel. 1, Created)
Date            17-Jan-2008 (Last updated)
IDR fact file   FF149.xml
OMIM            186780
Gene            CD247
IDbase          CD247base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         CD3gamma deficiency
Accession       I0137
Date            17-Jan-2008 (Rel. 1, Created)
Date            17-Jan-2008 (Last updated)
IDR fact file   FF149.xml
OMIM            186780
Gene            CD3G
IDbase          CD3Gbase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Cernunnos deficiency
Accession       I0138
Date            17-Jan-2008 (Rel. 1, Created)
Date            17-Jan-2008 (Last updated)
IDR fact file   FF125.xml
OMIM            611290
Gene            NHEJ1
IDbase          NHEJ1base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         DNA ligase 4 deficiency
Accession       I0139
Date            17-Jan-2008 (Rel. 1, Created)
Date            17-Jan-2008 (Last updated)
IDR fact file   FF118.xml
OMIM            601837
Gene            LIG4
IDbase          LIG4base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         MHC class II deficiency/RFXANK
Accession       I0140
Date            17-Jan-2008 (Rel. 1, Created)
Date            17-Jan-2008 (Last updated)
IDR fact file   FF15.xml
OMIM            603200
Gene            RFXANK
IDbase          RFXANKbase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         MHC class II deficiency/RFX5
Accession       I0141
Date            17-Jan-2008 (Rel. 1, Created)
Date            17-Jan-2008 (Last updated)
IDR fact file   FF13
OMIM            601863
Gene            RFX5
IDbase          RFX5base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         MHC class II deficiency/RFXAP
Accession       I0142
Date            17-Jan-2008 (Rel. 1, Created)
Date            17-Jan-2008 (Last updated)
IDR fact file   FF14
OMIM            601861
Gene            RFXAP
IDbase          RFXAPbase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         MHC class II deficiency/CIITA
Accession       I0143
Date            17-Jan-2008 (Rel. 1, Created)
Date            17-Jan-2008 (Last updated)
IDR fact file   FF12
OMIM            600005
Gene            CIITA
IDbase          CIITAbase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         TAP1 deficiency
Accession       I0144
Date            17-Jan-2008 (Rel. 1, Created)
Date            17-Jan-2008 (Last updated)
IDR fact file   FF107.xml
OMIM            170260
Gene            TAP1
IDbase          TAP1base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         TAP2 deficiency
Accession       I0145
Date            17-Jan-2008 (Rel. 1, Created)
Date            17-Jan-2008 (Last updated)
IDR fact file   FF60.xml
OMIM            170261
Gene            TAP2
IDbase          TAP2base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         WHN (FOXN1) deficiency
Accession       I0146
Date            17-Jan-2008 (Rel. 1, Created)
Date            17-Jan-2008 (Last updated)
IDR fact file   FF128.xml
OMIM            600838
Gene            FOXN1
IDbase          FOXN1base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         SCID with CRAC channel dysfunction/TMEM142A
Accession       I0147
Date            17-Jan-2008 (Rel. 1, Created)
Date            17-Jan-2008 (Last updated)
IDR fact file   FF147.xml
OMIM            610277
Gene            ORAI1
IDbase          ORAI1base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Adenosine deaminase deficiency
Accession       I0148
Date            17-Jan-2008 (Rel. 1, Created)
Date            17-Jan-2008 (Last updated)
IDR fact file   FF10.xml
OMIM            102700
Gene            ADA
IDbase          ADAbase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Purine nucleoside phosphorylase deficiency
Accession       I0149
Date            17-Jan-2008 (Rel. 1, Created)
Date            17-Jan-2008 (Last updated)
IDR fact file   FF11.xml
OMIM            164050
Gene            NP
IDbase          NPbase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Wiskott-Aldrich syndrome and X-linked thrombocytopenia
Accession       I0150
Date            17-Jan-2008 (Rel. 1, Created)
Date            17-Jan-2008 (Last updated)
IDR fact file   FF71.xml
OMIM            300392
Gene            WAS
IDbase          WASbase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         X-linked hyper-IgM syndrome/CD40LG
Accession       I0151
Date            17-Jan-2008 (Rel. 1, Created)
Date            17-Jan-2008 (Last updated)
IDR factfile    FF16.xml          
OMIM            300386
Gene            TNFSF5
IDbase          TNFSF5base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Autoimmune polyendocrinopathy with candidiasis and 
Disease         ectodermal dystrophy
Accession       I0152
Date            17-Jan-2008 (Rel. 1, Created)
Date            17-Jan-2008 (Last updated)
IDR fact file   FF72.xml
OMIM            607358
Gene            AIRE
IDbase          AIREbase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         X-linked agammaglobulinemia
Accession       I0153
Date            17-Jan-2008 (Rel. 1, Created)
Date            17-Jan-2008 (Last updated)
IDR fact file   FF22.xml
OMIM            300300
Gene            BTK
IDbase          BTKbase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         WHIM syndrome
Accession       I0154
Date            17-Jan-2008 (Rel. 1, Created)
Date            17-Jan-2008 (Last updated)
IDR fact file   FF7.xml
OMIM            162643
Gene            CXCR4
IDbase          CXCR4base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         X-linked hyper-IgM syndrome and hypohydrotic ectodermal 
Disease         dysplasia (Nemo deficiency)
Accession       I0155
Date            17-Jan-2008 (Rel. 1, Created)
Date            17-Jan-2008 (Last updated)
IDR fact file   FF19.xml
OMIM            300248
Gene            IKBKG
IDbase          IKBKGbase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         X-linked lymphoproliferative syndrome (Duncan disease)
Accession       I0156
Date            17-Jan-2008 (Rel. 1, Created)
Date            17-Jan-2008 (Last updated)
IDR fact file   FF73.xml
OMIM            300490
Gene            SH2D1A
IDbase          SH2D1Abase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         TAP1 deficiency
Accession       I0157
Date            17-Jan-2008 (Rel. 1, Created)
Date            17-Jan-2008 (Last updated)
IDR fact file   FF107.xml
OMIM            170260
Gene            TAP1
IDbase          TAP1base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         TAP2 deficiency
Accession       I0158
Date            17-Jan-2008 (Rel. 1, Created)
Date            17-Jan-2008 (Last updated)
IDR fact file   FF60.xml
OMIM            170261
Gene            TAP2
IDbase          TAP2base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         ZAP-70 deficiency
Accession       I0159
Date            17-Jan-2008 (Rel. 1, Created)
Date            17-Jan-2008 (Last updated)
IDR fact file   FF62.xml
OMIM            176947
Gene            ZAP70
IDbase          ZAP70base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599 
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         mu heavy-chain deficiency
Accession       I0160
Date            21-Jan-2008 (Rel. 1, Created)
Date            21-Jan-2008 (Last updated)
IDR fact file   FF26.xml
OMIM            147020
Gene            IGHM
IDbase          IGHMbase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         lambda5 surrogate light-chain deficiency
Accession       I0161
Date            21-Jan-2008 (Rel. 1, Created)
Date            21-Jan-2008 (Last updated)
IDR fact file   FF27.xml
OMIM            146770
Gene            IGLL1
IDbase          IGLL1base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.

//
Disease         Igalpha deficiency
Accession       I0162
Date            21-Jan-2008 (Rel. 1, Created)
Date            21-Jan-2008 (Last updated)
IDR fact file   FF25.xml
OMIM            112205
Gene            CD79A
IDbase          CD79Abase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         BLNK deficiency
Accession       I0163
Date            21-Jan-2008 (Rel. 1, Created)
Date            21-Jan-2008 (Last updated)
IDR fact file   FF24.xml
OMIM            604515
Gene            BLNK
IDbase          BLNKbase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Agammaglobulinemia, non-Bruton type, autosomal 
Disease         dominant/LRRC8A
Accession       I0164
Date            21-Jan-2008 (Rel. 1, Created)
Date            21-Jan-2008 (Last updated)
IDR fact file   FF151.xml
OMIM            608360
Gene            LRRC8A
IDbase          LRRC8Abase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         CD40 deficiency
Accession       I0165
Date            22-Jan-2008 (Rel. 1, Created)
Date            22-Jan-2008 (Last updated)
IDR fact file   FF18.xml
OMIM            109535
Gene            TNFRSF5
IDbase          TNFRSF5base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Non-X-linked hyper-IgM syndrome
Accession       I0166
Date            22-Jan-2008 (Rel. 1, Created)
Date            22-Jan-2008 (Last updated)
IDR fact file   FF17.xml
OMIM            605257
Gene            AICDA
IDbase          AICDAbase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         UNG deficiency (Hyper-IgM syndrome, type 5)
Accession       I0167
Date            22-Jan-2008 (Rel. 1, Created)
Date            22-Jan-2008 (Last updated)
IDR fact file   FF127.xml
OMIM            191525
Gene            UNG
IDbase          UNGbase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Ataxia-telengiectasia
Accession       I0168
Date            22-Jan-2008 (Rel. 1, Created)
Date            22-Jan-2008 (Last updated)
IDR fact file   FF87.xml
OMIM            607585
Gene            ATM
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Nijmegen-breakage syndrome
Accession       I0169
Date            22-Jan-2008 (Rel. 1, Created)
Date            22-Jan-2008 (Last updated)
IDR fact file   FF88.xml
OMIM            602667
Gene            NBS1
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Ataxia-telangiectasia-like disorder (ATLD)
Accession       I0170
Date            22-Jan-2008 (Rel. 1, Created)
Date            22-Jan-2008 (Last updated)
IDR fact file   FF120.xml
OMIM            600814
Gene            MRE11A
IDbase          MRE11Abase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Hermansky-Pudlak syndrome 2
Accession       I0171
Date            22-Jan-2008 (Rel. 1, Created)
Date            22-Jan-2008 (Last updated)
IDR fact file   FF108.xml
OMIM            603401
Gene            AP3B1
IDbase          AP3B1base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Hyper-IgE syndrome/TYK2
Accession       I0172
Date            22-Jan-2008 (Rel. 1, Created)
Date            22-Jan-2008 (Last updated)
IDR fact file   FF163
OMIM            176941  
Gene            TYK2
IDbase          TYK2base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Hyper-IgE syndrome/STAT3
Accession       I0173
Date            22-Jan-2008 (Rel. 1, Created)
Date            22-Jan-2008 (Last updated)
IDR fact file   FF167          
OMIM            102582
Gene            STAT3
IDbase          STAT3base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Immunodeficiency, centromere instability and facial 
Disease         abnormalities syndrome (ICF)
Accession       I0174
Date            22-Jan-2008 (Rel. 1, Created)
Date            22-Jan-2008 (Last updated)
IDR fact file   FF124.xml
OMIM            602900
Gene            DNMT3B
IDbase          DNMT3Bbase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Chediak-Higashi syndrome
Accession       I0175
Date            22-Jan-2008 (Rel. 1, Created)
Date            22-Jan-2008 (Last updated)
IDR fact file   FF79.xml
OMIM            606897
Gene            LYST
IDbase          LYSTbase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Griscelli syndrome, type 1
Accession       I0176
Date            22-Jan-2008 (Rel. 1, Created)
Date            22-Jan-2008 (Last updated)
IDR fact file   FF80.xml
OMIM            160777
Gene            MYO5A
IDbase          MYO5Abase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Griscelli syndrome, type 2
Accession       I0177
Date            22-Jan-2008 (Rel. 1, Created)
Date            22-Jan-2008 (Last updated)
IDR fact file   FF122.xml
OMIM            603868
Gene            RAB27A
IDbase          RABD27Abase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Familial hemophagocytic lymphohistiocytosis type 2
Accession       I0178
Date            22-Jan-2008 (Rel. 1, Created)
Date            22-Jan-2008 (Last updated)
IDR fact file   FF105.xml
OMIM            170280
Gene            PRF1
IDbase          PRF1base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Familial hemophagocytic lymphohistiocytosis type 3
Accession       I0179
Date            22-Jan-2008 (Rel. 1, Created)
Date            22-Jan-2008 (Last updated)
IDR fact file   FF126.xml
OMIM            608898
Gene            UNC13D
IDbase          UNC13Dbase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Familial hemophagocytic lymphohistiocytosis type 3
Accession       I0180
Date            22-Jan-2008 (Rel. 1, Created)
Date            22-Jan-2008 (Last updated)
IDR fact file   FF155.xml
OMIM            605014
Gene            STX11
IDbase          STX11base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         X-linked lymphoproliferative syndrome (Duncan disease)
Accession       I0181
Date            22-Jan-2008 (Rel. 1, Created)
Date            22-Jan-2008 (Last updated)
IDR fact file   FF73.xml
OMIM            300490
Gene            SH2D1A
IDbase          SH2D1Abase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         X-linked lymphoproliferative syndrome 2/BIRC4
Accession       I0182
Date            22-Jan-2008 (Rel. 1, Created)
Date            22-Jan-2008 (Last updated)
IDR fact file   FF165.xml
OMIM            300079
Gene            BIRC4
IDbase          BIRC4base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Omenn syndrome
Accession       I0183
Date            22-Jan-2008 (Rel. 1, Created)
Date            22-Jan-2008 (Last updated)
IDR fact file   FF4.xml
OMIM            603554
Gene            RAG1
IDbase          RAG1base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Omenn syndrome
Accession       I0184
Date            22-Jan-2008 (Rel. 1, Created)
Date            22-Jan-2008 (Last updated)
IDR fact file   FF4.xml
OMIM            603554
Gene            RAG2
IDbase          RAG2base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Artemis deficiency/DCLRE1C
Accession       I0185
Date            22-Jan-2008 (Rel. 1, Created)
Date            22-Jan-2008 (Last updated)
IDR fact file   FF5.xml
OMIM            605988
Gene            DCLRE1C
IDbases         DCLRE1Cbase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Omenn syndrome/IL7R
Accession       I0186
Date            22-Jan-2008 (Rel. 1, Created)
Date            22-Jan-2008 (Last updated)
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         ICOS deficiency
Accession       I0187
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
IDR fact file   FF116.xml
OMIM            604558
Gene            ICOS
IDbase          ICOSbase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         CD19 deficiency/CD19
Accession       I0188
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
IDR fact file   FF150.xml
OMIM            107265
Gene            CD19
IDbase          CD19base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         TNFRSF13B deficiency
Accession       I0189
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
IDR fact file   FF150.xml
OMIM            107265
Gene            TNFRSF13B
IDbase          TNFRSF13Bbase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Autoimmune lymphoproliferative syndrome, type 1A
Accession       I0190
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
IDR fact file   FF36.xml
OMIM            134637
Gene            TNFRSF6
IDbase          TNFRSF6base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Autoimmune lymphoproliferative syndrome, type 1B
Accession       I0191
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
IDR fact file   FF37.xml
OMIM            134638
Gene            TNFSF6
IDbase          TNFSF6base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Caspase 8 deficiency/Autoimmune lymphoproliferative 
Disease         syndrome type IIB
Accession       I0192
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
IDR fact file   FF110.xml
OMIM            601763
Gene            CASP8
IDbase          CASP8base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Caspase 10 deficiency/Autoimmune lymphoproliferative 
Disease         syndrome type II
Accession       I0193
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
IDR fact file   FF109.xml
OMIM            601762
Gene            CASP10
IDbase          CASP10base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Cartilage-hair hypoplasia
Accession       I0194
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
IDR fact file   FF77.xml
OMIM            157660
Gene            RMRP
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Immunodeficiency, polyendocrinopathy, enteropathy, X-linked
Accession       I0195
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
IDR fact file   FF78.xml
OMIM            300292
Gene            FOXP3
IDbase          FOXP3base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Ectodermal anhydrotic dysplasia with T-cell 
Disease         immunodeficiency/NFKBIA
Accession       I0196
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
IDR fact file   FF121.xml
OMIM            164008
Gene            NFKBIA
IDbase          NFKBIAbase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Ectodermal anhydrotic dysplasia with immunodeficiency/IKBKG
Accession       I0197
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Incontinentia pigmenti/IKBKG
Accession       I0198
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         IRAK4 deficiency
Accession       I0199
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
IDR fact file   FF117.xml
OMIM            606883
Gene            IRAK4
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         WHIM syndrome
Accession       I0200
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
IDR fact file   FF7.xml
OMIM            162643
Gene            CXCR4
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Epidermodysplasia verruciformis type 1
Accession       I0201
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
IDR fact file   FF114.xml
OMIM            605828
Gene            EVER1
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Epidermodysplasia verruciformis type 2
Accession       I0202
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
IDR fact file   FF115.xml
OMIM            605829
Gene            EVER2
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Cyclic neutropenia
Accession       I0203
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
IDR fact file   FF86.xml
OMIM            130130
Gene            ELA2
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         GFI1 deficiency
Accession       I0204
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
IDR fact file   FF129.xml
OMIM            600871
Gene            GFI1
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Severe congenital neutropenias, including Kostmann syndrome
Accession       I0205
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
IDR fact file   FF85.xml
OMIM            130130
Gene            CSF3R
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Shwachman-Diamond syndrome/SBDS
Accession       I0206
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         X-linked chronic granulomatous disease
Accession       I0207
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
IDR fact file   FF38.xml
OMIM            300481
Gene            CYBB
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Autosomal chronic granulomatous disease/CYBA
Accession       I0208
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Autosomal chronic granulomatous disease/NCF1
Accession       I0209
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Autosomal chronic granulomatous disease/NCF2
Accession       I0210
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Interleukin-12 receptor beta1 deficiency
Accession       I0211
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
IDR fact file   FF47.xml
OMIM            601604
Gene            IL12RB1
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Interleukin-12 (IL-12) p40 deficiency
Accession       I0212
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
IDR fact file   FF46.xml
OMIM            161561
Gene            IL12B
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         IFNgamma1-receptor deficiency
Accession       I0213
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
IDR fact file   FF44.xml
OMIM            107470
Gene            IFNGR1
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         IFNgamma2-receptor deficiency
Accession       I0214
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
IDR fact file   FF45.xml
OMIM            147569
Gene            IFNGR2
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         STAT1 deficiency
Accession       I0215
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
IDR fact file   FF70.xml
OMIM            600555
Gene            STAT1
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Leukocyte adhesion deficiency I
Accession       I0216
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
IDR fact file   FF42.xml
OMIM            600065
Gene            ITGB2
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Leukocyte adhesion deficiency II
Accession       I0217
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
IDR fact file   FF43.xml
OMIM            605881
Gene            SLC35C1
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Leukocyte adhesion deficiency II
Accession       I0218
Date            23-Jan-2008 (Rel. 1, Created)
Date            23-Jan-2008 (Last updated)
IDR fact file   FF43.xml
OMIM            605881
Gene            SLC35C1
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Crohn disease/NOD2
Accession       I0219
Date            24-Jan-2008 (Rel. 1, Created)
Date            24-Jan-2008 (Last updated)
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599         
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Blau syndrome/NOD2
Accession       I0220
Date            24-Jan-2008 (Rel. 1, Created)
Date            24-Jan-2008 (Last updated)
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599         
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Hepatic venoocclusive disease with immunodeficiency/SP110
Accession       I0221
Date            25-Jan-2008 (Rel. 1, Created)
Date            25-Jan-2008 (Last updated)
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         STAT1 deficiency
Accession       I0222
Date            25-Jan-2008 (Rel. 1, Created)
Date            25-Jan-2008 (Last updated)
IDR fact file   FF70.xml
OMIM            600555
Gene            STAT1
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Growth hormone insensitivity with immunodeficiency
Accession       I0223
Date            25-Jan-2008 (Rel. 1, Created)
Date            25-Jan-2008 (Last updated)
IDR fact file   FF125.xml
OMIM            604260
Gene            STAT5B
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         C8 alpha-polypeptide deficiency
Accession       I0224
Date            25-Jan-2008 (Rel. 1, Created)
Date            25-Jan-2008 (Last updated)
IDR fact file   FF55.xml
OMIM            120950
Gene            C8A
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         T-cell immunodeficiency, congenital alopecia, and nail    
Disease         dystrophy/WHN
Accession       I0225
Date            25-Jan-2008 (Rel. 1, Created)
Date            25-Jan-2008 (Last updated
IDR fact file   FF128.xml
OMIM            600838
Gene            FOXN1
IDbase          FOXN1base
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany        
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Non-X-linked hyper-IgM syndrome
Accession       I0227
Date            07-Feb-2008 (Rel. 1, Created)
Date            07-Feb-2008 (Last updated)
IDR fact file   FF17.xml
OMIM            605257
Gene            AICDA
IDbase          AICDAbase
Contact         Romina LeBlanc, M.S., MBA
Address         Correlagen Diagnostics, Inc.
Address         307 Waverley Oaks Road Suite 101 Waltham, MA 02452, USA
Telephone       1-617-851-3769
Fax             1-617-812-6426
Email           rleblanc@correlagen.com
URL             www.correlagen.com
Method          Direct sequencing; Additionally we offer carrier testing 
Method          and known mutation analysis
Frequency       As needed
Turnaround      2-4 weeks
Price           Available upon request
Comment         Correlagen Diagnostics, Inc. is a CLIA certified and CAP
Comment         accredited clinical laboratory in United States. Our
Comment         company’s mission is to promote use of clinically
Comment         appropriate genetic testing to facilitate the diagnosis and
Comment         treatment of Primary Immunodeficiency Diseases. We offer
Comment         high-quality, cost-effective, full-length gene sequencing
Comment         tests, with rapid turn-around times and comprehensive and
Comment         user-friendly reporting.
//
Disease         Adenosine deaminase deficiency
Accession       I0228
Date            07-Feb-2008 (Rel. 1, Created)
Date            07-Feb-2008 (Last updated)
IDR fact file   FF10.xml
OMIM            102700
Gene            ADA
IDbase          ADAbase
Contact         Romina LeBlanc, M.S., MBA
Address         Correlagen Diagnostics, Inc.
Address         307 Waverley Oaks Road Suite 101 Waltham, MA 02452, USA
Telephone       1-617-851-3769
Fax             1-617-812-6426
Email           rleblanc@correlagen.com
URL             www.correlagen.com
Method          Direct sequencing; Additionally we offer carrier testing 
Method          and known mutation analysis
Frequency       As needed
Turnaround      2-4 weeks
Price           Available upon request
Comment         Correlagen Diagnostics, Inc. is a CLIA certified and CAP
Comment         accredited clinical laboratory in United States. Our
Comment         company’s mission is to promote use of clinically
Comment         appropriate genetic testing to facilitate the diagnosis and
Comment         treatment of Primary Immunodeficiency Diseases. We offer
Comment         high-quality, cost-effective, full-length gene sequencing
Comment         tests, with rapid turn-around times and comprehensive and
Comment         user-friendly reporting.
//
Disease         Artemis deficiency
Accession       I0229
Date            07-Feb-2008 (Rel. 1, Created)
Date            07-Feb-2008 (Last updated)
IDR fact file   FF5.xml
OMIM            605988
Gene            DCLRE1C
IDbase          DCLRE1Cbase
Contact         Romina LeBlanc, M.S., MBA
Address         Correlagen Diagnostics, Inc.
Address         307 Waverley Oaks Road Suite 101 Waltham, MA 02452, USA
Telephone       1-617-851-3769
Fax             1-617-812-6426
Email           rleblanc@correlagen.com
URL             www.correlagen.com
Method          Direct sequencing; Additionally we offer carrier testing 
Method          and known mutation analysis
Frequency       As needed
Turnaround      2-4 weeks
Price           Available upon request
Comment         Correlagen Diagnostics, Inc. is a CLIA certified and CAP
Comment         accredited clinical laboratory in United States. Our
Comment         company’s mission is to promote use of clinically
Comment         appropriate genetic testing to facilitate the diagnosis and
Comment         treatment of Primary Immunodeficiency Diseases. We offer
Comment         high-quality, cost-effective, full-length gene sequencing
Comment         tests, with rapid turn-around times and comprehensive and
Comment         user-friendly reporting.
//
Disease         Autoimmune polyendocrinopathy with candidiasis and 
Disease         ectodermal dystrophy
Accession       I0230
Date            07-Feb-2008 (Rel. 1, Created)
Date            07-Feb-2008 (Last updated)
IDR fact file   FF72.xml
OMIM            607358
Gene            AIRE
IDbase          AIREbase
Contact         Romina LeBlanc, M.S., MBA
Address         Correlagen Diagnostics, Inc.
Address         307 Waverley Oaks Road Suite 101 Waltham, MA 02452, USA
Telephone       1-617-851-3769
Fax             1-617-812-6426
Email           rleblanc@correlagen.com
URL             www.correlagen.com
Method          Direct sequencing; Additionally we offer carrier testing 
Method          and known mutation analysis
Frequency       As needed
Turnaround      2-4 weeks
Price           Available upon request
Comment         Correlagen Diagnostics, Inc. is a CLIA certified and CAP
Comment         accredited clinical laboratory in United States. Our
Comment         company’s mission is to promote use of clinically
Comment         appropriate genetic testing to facilitate the diagnosis and
Comment         treatment of Primary Immunodeficiency Diseases. We offer
Comment         high-quality, cost-effective, full-length gene sequencing
Comment         tests, with rapid turn-around times and comprehensive and
Comment         user-friendly reporting.
//
Disease         CD3delta deficiency
Accession       I0231
Date            07-Feb-2008 (Rel. 1, Created)
Date            07-Feb-2008 (Last updated)
IDR fact file   FF111.xml
OMIM            186790
Gene            CD3D
IDbase          CD3Dbase
Contact         Romina LeBlanc, M.S., MBA
Address         Correlagen Diagnostics, Inc.
Address         307 Waverley Oaks Road Suite 101 Waltham, MA 02452, USA
Telephone       1-617-851-3769
Fax             1-617-812-6426
Email           rleblanc@correlagen.com
URL             www.correlagen.com
Method          Direct sequencing; Additionally we offer carrier testing 
Method          and known mutation analysis
Frequency       As needed
Turnaround      2-4 weeks
Price           Available upon request
Comment         Correlagen Diagnostics, Inc. is a CLIA certified and CAP
Comment         accredited clinical laboratory in United States. Our
Comment         company’s mission is to promote use of clinically
Comment         appropriate genetic testing to facilitate the diagnosis and
Comment         treatment of Primary Immunodeficiency Diseases. We offer
Comment         high-quality, cost-effective, full-length gene sequencing
Comment         tests, with rapid turn-around times and comprehensive and
Comment         user-friendly reporting.
//
Disease         CD3epsilon deficiency
Accession       I0232
Date            07-Feb-2008 (Rel. 1, Created)
Date            07-Feb-2008 (Last updated)
IDR fact file   FF20.xml
OMIM            186830
Gene            CD3E
IDbase          CDREbase
Contact         Romina LeBlanc, M.S., MBA
Address         Correlagen Diagnostics, Inc.
Address         307 Waverley Oaks Road Suite 101 Waltham, MA 02452, USA
Telephone       1-617-851-3769
Fax             1-617-812-6426
Email           rleblanc@correlagen.com
URL             www.correlagen.com
Method          Direct sequencing; Additionally we offer carrier testing 
Method          and known mutation analysis
Frequency       As needed
Turnaround      2-4 weeks
Price           Available upon request
Comment         Correlagen Diagnostics, Inc. is a CLIA certified and CAP
Comment         accredited clinical laboratory in United States. Our
Comment         company’s mission is to promote use of clinically
Comment         appropriate genetic testing to facilitate the diagnosis and
Comment         treatment of Primary Immunodeficiency Diseases. We offer
Comment         high-quality, cost-effective, full-length gene sequencing
Comment         tests, with rapid turn-around times and comprehensive and
Comment         user-friendly reporting.
//
Disease         CD40 deficiency
Accession       I0233
Date            07-Feb-2008 (Rel. 1, Created)
Date            07-Feb-2008 (Last updated)
IDR fact file   FF18.xml
OMIM            109535
Gene            TNFRSF5
IDbase          CD40base
Contact         Romina LeBlanc, M.S., MBA
Address         Correlagen Diagnostics, Inc.
Address         307 Waverley Oaks Road Suite 101 Waltham, MA 02452, USA
Telephone       1-617-851-3769
Fax             1-617-812-6426
Email           rleblanc@correlagen.com
URL             www.correlagen.com
Method          Direct sequencing; Additionally we offer carrier testing 
Method          and known mutation analysis
Frequency       As needed
Turnaround      2-4 weeks
Price           Available upon request
Comment         Correlagen Diagnostics, Inc. is a CLIA certified and CAP
Comment         accredited clinical laboratory in United States. Our
Comment         company’s mission is to promote use of clinically
Comment         appropriate genetic testing to facilitate the diagnosis and
Comment         treatment of Primary Immunodeficiency Diseases. We offer
Comment         high-quality, cost-effective, full-length gene sequencing
Comment         tests, with rapid turn-around times and comprehensive and
Comment         user-friendly reporting.
//
Disease         IFNgamma1-receptor deficiency
Accession       I0234
Date            07-Feb-2008 (Rel. 1, Created)
Date            07-Feb-2008 (Last updated)
IDR fact file   FF44.xml
OMIM            107470
Gene            IFNGR1
IDbase          IFNGR1base
Contact         Romina LeBlanc, M.S., MBA
Address         Correlagen Diagnostics, Inc.
Address         307 Waverley Oaks Road Suite 101 Waltham, MA 02452, USA
Telephone       1-617-851-3769
Fax             1-617-812-6426
Email           rleblanc@correlagen.com
URL             www.correlagen.com
Method          Direct sequencing; Additionally we offer carrier testing 
Method          and known mutation analysis
Frequency       As needed
Turnaround      2-4 weeks
Price           Available upon request
Comment         Correlagen Diagnostics, Inc. is a CLIA certified and CAP
Comment         accredited clinical laboratory in United States. Our
Comment         company’s mission is to promote use of clinically
Comment         appropriate genetic testing to facilitate the diagnosis and
Comment         treatment of Primary Immunodeficiency Diseases. We offer
Comment         high-quality, cost-effective, full-length gene sequencing
Comment         tests, with rapid turn-around times and comprehensive and
Comment         user-friendly reporting.
//
Disease         IFNgamma2-receptor deficiency
Accession       I0235
Date            07-Feb-2008 (Rel. 1, Created)
Date            07-Feb-2008 (Last updated)
IDR fact file   FF45.xml
OMIM            147569
Gene            IFNGR2
IDbase          IFNGR2base
Contact         Romina LeBlanc, M.S., MBA
Address         Correlagen Diagnostics, Inc.
Address         307 Waverley Oaks Road Suite 101 Waltham, MA 02452, USA
Telephone       1-617-851-3769
Fax             1-617-812-6426
Email           rleblanc@correlagen.com
URL             www.correlagen.com
Method          Direct sequencing; Additionally we offer carrier testing 
Method          and known mutation analysis
Frequency       As needed
Turnaround      2-4 weeks
Price           Available upon request
Comment         Correlagen Diagnostics, Inc. is a CLIA certified and CAP
Comment         accredited clinical laboratory in United States. Our
Comment         company’s mission is to promote use of clinically
Comment         appropriate genetic testing to facilitate the diagnosis and
Comment         treatment of Primary Immunodeficiency Diseases. We offer
Comment         high-quality, cost-effective, full-length gene sequencing
Comment         tests, with rapid turn-around times and comprehensive and
Comment         user-friendly reporting.
//
Disease         Interleukin 7 receptor deficiency
Accession       I0236
Date            08-Feb-2008 (Rel. 1, Created)
Date            08-Feb-2008 (Last updated)
IDR fact file   FF106.xml
OMIM            146661
Gene            IL7R
IDbase          IL7Rbase
Contact         Romina LeBlanc, M.S., MBA
Address         Correlagen Diagnostics, Inc.
Address         307 Waverley Oaks Road Suite 101 Waltham, MA 02452, USA
Telephone       1-617-851-3769
Fax             1-617-812-6426
Email           rleblanc@correlagen.com
URL             www.correlagen.com
Method          Direct sequencing; Additionally we offer carrier testing 
Method          and known mutation analysis
Frequency       As needed
Turnaround      2-4 weeks
Price           Available upon request
Comment         Correlagen Diagnostics, Inc. is a CLIA certified and CAP
Comment         accredited clinical laboratory in United States. Our
Comment         company’s mission is to promote use of clinically
Comment         appropriate genetic testing to facilitate the diagnosis and
Comment         treatment of Primary Immunodeficiency Diseases. We offer
Comment         high-quality, cost-effective, full-length gene sequencing
Comment         tests, with rapid turn-around times and comprehensive and
Comment         user-friendly reporting.
//
Disease         JAK3 deficiency
Accession       I0237
Date            08-Feb-2008 (Rel. 1, Created)
Date            08-Feb-2008 (Last updated)
IDR fact file   FF9.xml
OMIM            600173
Gene            JAK3
IDbase          JAK3base
Contact         Romina LeBlanc, M.S., MBA
Address         Correlagen Diagnostics, Inc.
Address         307 Waverley Oaks Road Suite 101 Waltham, MA 02452, USA
Telephone       1-617-851-3769
Fax             1-617-812-6426
Email           rleblanc@correlagen.com
URL             www.correlagen.com
Method          Direct sequencing; Additionally we offer carrier testing 
Method          and known mutation analysis
Frequency       As needed
Turnaround      2-4 weeks
Price           Available upon request
Comment         Correlagen Diagnostics, Inc. is a CLIA certified and CAP
Comment         accredited clinical laboratory in United States. Our
Comment         company’s mission is to promote use of clinically
Comment         appropriate genetic testing to facilitate the diagnosis and
Comment         treatment of Primary Immunodeficiency Diseases. We offer
Comment         high-quality, cost-effective, full-length gene sequencing
Comment         tests, with rapid turn-around times and comprehensive and
Comment         user-friendly reporting.
//
Disease         Omenn syndrome
Accession       I0238
Date            08-Feb-2008 (Rel. 1, Created)
Date            08-Feb-2008 (Last updated)
IDR fact file   FF4.xml
OMIM            603554
Gene            RAG2
IDbase          RAG2base
Contact         Romina LeBlanc, M.S., MBA
Address         Correlagen Diagnostics, Inc.
Address         307 Waverley Oaks Road Suite 101 Waltham, MA 02452, USA
Telephone       1-617-851-3769
Fax             1-617-812-6426
Email           rleblanc@correlagen.com
URL             www.correlagen.com
Method          Direct sequencing; Additionally we offer carrier testing 
Method          and known mutation analysis
Frequency       As needed
Turnaround      2-4 weeks
Price           Available upon request
Comment         Correlagen Diagnostics, Inc. is a CLIA certified and CAP
Comment         accredited clinical laboratory in United States. Our
Comment         company’s mission is to promote use of clinically
Comment         appropriate genetic testing to facilitate the diagnosis and
Comment         treatment of Primary Immunodeficiency Diseases. We offer
Comment         high-quality, cost-effective, full-length gene sequencing
Comment         tests, with rapid turn-around times and comprehensive and
Comment         user-friendly reporting
//
Disease         RAG2 deficiency
Accession       I0239
Date            08-Feb-2008 (Rel. 1, Created)
Date            08-Feb-2008 (Last updated)
IDR fact file   FF3.xml
OMIM            179616
Gene            RAG2
IDbase          RAG1base
Contact         Romina LeBlanc, M.S., MBA
Address         Correlagen Diagnostics, Inc.
Address         307 Waverley Oaks Road Suite 101 Waltham, MA 02452, USA
Telephone       1-617-851-3769
Fax             1-617-812-6426
Email           rleblanc@correlagen.com
URL             www.correlagen.com
Method          Direct sequencing; Additionally we offer carrier testing 
Method          and known mutation analysis
Frequency       As needed
Turnaround      2-4 weeks
Price           Available upon request
Comment         Correlagen Diagnostics, Inc. is a CLIA certified and CAP
Comment         accredited clinical laboratory in United States. Our
Comment         company’s mission is to promote use of clinically
Comment         appropriate genetic testing to facilitate the diagnosis and
Comment         treatment of Primary Immunodeficiency Diseases. We offer
Comment         high-quality, cost-effective, full-length gene sequencing
Comment         tests, with rapid turn-around times and comprehensive and
Comment         user-friendly reporting.
//
Disease         Omenn syndrome
Accession       I0240
Date            08-Feb-2008 (Rel. 1, Created)
Date            08-Feb-2008 (Last updated)
IDR fact file   FF4.xml
OMIM            603554
Gene            RAG1
IDbase          RAG1base
Contact         Romina LeBlanc, M.S., MBA
Address         Correlagen Diagnostics, Inc.
Address         307 Waverley Oaks Road Suite 101 Waltham, MA 02452, USA
Telephone       1-617-851-3769
Fax             1-617-812-6426
Email           rleblanc@correlagen.com
URL             www.correlagen.com
Method          Direct sequencing; Additionally we offer carrier testing 
Method          and known mutation analysis
Frequency       As needed
Turnaround      2-4 weeks
Price           Available upon request
Comment         Correlagen Diagnostics, Inc. is a CLIA certified and CAP
Comment         accredited clinical laboratory in United States. Our
Comment         company’s mission is to promote use of clinically
Comment         appropriate genetic testing to facilitate the diagnosis and
Comment         treatment of Primary Immunodeficiency Diseases. We offer
Comment         high-quality, cost-effective, full-length gene sequencing
Comment         tests, with rapid turn-around times and comprehensive and
Comment         user-friendly reporting.
//
Disease         UNG deficiency (Hyper-IgM syndrome, type 5)
Accession       I0241
Date            08-Feb-2008 (Rel. 1, Created)
Date            08-Feb-2008 (Last updated)
IDR fact file   FF127.xml
OMIM            191525
Gene            UNG
IDbase          UNGbase
Contact         Romina LeBlanc, M.S., MBA
Address         Correlagen Diagnostics, Inc.
Address         307 Waverley Oaks Road Suite 101 Waltham, MA 02452, USA
Telephone       1-617-851-3769
Fax             1-617-812-6426
Email           rleblanc@correlagen.com
URL             www.correlagen.com
Method          Direct sequencing; Additionally we offer carrier testing 
Method          and known mutation analysis
Frequency       As needed
Turnaround      2-4 weeks
Price           Available upon request
Comment         Correlagen Diagnostics, Inc. is a CLIA certified and CAP
Comment         accredited clinical laboratory in United States. Our
Comment         company’s mission is to promote use of clinically
Comment         appropriate genetic testing to facilitate the diagnosis and
Comment         treatment of Primary Immunodeficiency Diseases. We offer
Comment         high-quality, cost-effective, full-length gene sequencing
Comment         tests, with rapid turn-around times and comprehensive and
Comment         user-friendly reporting.
//
Disease         Wiskott-Aldrich syndrome and X-linked thrombocytopenia
Accession       I0242
Date            08-Feb-2008 (Rel. 1, Created)
Date            08-Feb-2008 (Last updated)
IDR fact file   FF71.xml
OMIM            300392
Gene            WAS
IDbase          WASbase
Contact         Romina LeBlanc, M.S., MBA
Address         Correlagen Diagnostics, Inc.
Address         307 Waverley Oaks Road Suite 101 Waltham, MA 02452, USA
Telephone       1-617-851-3769
Fax             1-617-812-6426
Email           rleblanc@correlagen.com
URL             www.correlagen.com
Method          Direct sequencing; Additionally we offer carrier testing 
Method          and known mutation analysis
Frequency       As needed
Turnaround      2-4 weeks
Price           Available upon request
Comment         Correlagen Diagnostics, Inc. is a CLIA certified and CAP
Comment         accredited clinical laboratory in United States. Our
Comment         company’s mission is to promote use of clinically
Comment         appropriate genetic testing to facilitate the diagnosis and
Comment         treatment of Primary Immunodeficiency Diseases. We offer
Comment         high-quality, cost-effective, full-length gene sequencing
Comment         tests, with rapid turn-around times and comprehensive and
Comment         user-friendly reporting.
//
Disease         X-linked SCID(gammac-chain deficiency)
Accession       I0243
Date            08-Feb-2008 (Rel. 1, Created)
Date            08-Feb-2008 (Last updated)
IDR fact file   FF8.xml
OMIM            308380 
Gene            IL2RG
Contact         Romina LeBlanc, M.S., MBA
Address         Correlagen Diagnostics, Inc.
Address         307 Waverley Oaks Road Suite 101 Waltham, MA 02452, USA
Telephone       1-617-851-3769
Fax             1-617-812-6426
Email           rleblanc@correlagen.com
URL             www.correlagen.com
Method          Direct sequencing; Additionally we offer carrier testing 
Method          and known mutation analysis
Frequency       As needed
Turnaround      2-4 weeks
Price           Available upon request
Comment         Correlagen Diagnostics, Inc. is a CLIA certified and CAP
Comment         accredited clinical laboratory in United States. Our
Comment         company’s mission is to promote use of clinically
Comment         appropriate genetic testing to facilitate the diagnosis and
Comment         treatment of Primary Immunodeficiency Diseases. We offer
Comment         high-quality, cost-effective, full-length gene sequencing
Comment         tests, with rapid turn-around times and comprehensive and
Comment         user-friendly reporting.
//
Disease         X-linked agammaglobulinemia
Accession       I0244
Date            08-Feb-2008 (Rel. 1, Created)
Date            08-Feb-2008 (Last updated)
IDR fact file   FF22.xml
OMIM            300300
Gene            BTK
IDbase          BTKbase
Contact         Romina LeBlanc, M.S., MBA
Address         Correlagen Diagnostics, Inc.
Address         307 Waverley Oaks Road Suite 101 Waltham, MA 02452, USA
Telephone       1-617-851-3769
Fax             1-617-812-6426
Email           rleblanc@correlagen.com
URL             www.correlagen.com
Method          Direct sequencing; Additionally we offer carrier testing 
Method          and known mutation analysis
Frequency       As needed
Turnaround      2-4 weeks
Price           Available upon request
Comment         Correlagen Diagnostics, Inc. is a CLIA certified and CAP
Comment         accredited clinical laboratory in United States. Our
Comment         company’s mission is to promote use of clinically
Comment         appropriate genetic testing to facilitate the diagnosis and
Comment         treatment of Primary Immunodeficiency Diseases. We offer
Comment         high-quality, cost-effective, full-length gene sequencing
Comment         tests, with rapid turn-around times and comprehensive and
Comment         user-friendly reporting.
//
Disease         X-linked chronic granulomatous disease
Accession       I0245
Date            08-Feb-2008 (Rel. 1, Created)
Date            08-Feb-2008 (Last updated)
IDR fact file   FF38.xml
OMIM            300481
Gene            CYBB
IDbase          CYBBbase
Contact         Romina LeBlanc, M.S., MBA
Address         Correlagen Diagnostics, Inc.
Address         307 Waverley Oaks Road Suite 101 Waltham, MA 02452, USA
Telephone       1-617-851-3769
Fax             1-617-812-6426
Email           rleblanc@correlagen.com
URL             www.correlagen.com
Method          Direct sequencing; Additionally we offer carrier testing 
Method          and known mutation analysis
Frequency       As needed
Turnaround      2-4 weeks
Price           Available upon request
Comment         Correlagen Diagnostics, Inc. is a CLIA certified and CAP
Comment         accredited clinical laboratory in United States. Our
Comment         company’s mission is to promote use of clinically
Comment         appropriate genetic testing to facilitate the diagnosis and
Comment         treatment of Primary Immunodeficiency Diseases. We offer
Comment         high-quality, cost-effective, full-length gene sequencing
Comment         tests, with rapid turn-around times and comprehensive and
Comment         user-friendly reporting.
//
Disease         X-linked hyper-IgM syndrome and hypohydrotic ectodermal 
Disease         dysplasia (Nemo deficiency)
Accession       I0246
Date            08-Feb-2008 (Rel. 1, Created)
Date            08-Feb-2008 (Last updated)
IDR fact file   FF19.xml
OMIM            300248
Gene            IKBKG
IDbase          IKBKGbase
Contact         Romina LeBlanc, M.S., MBA
Address         Correlagen Diagnostics, Inc. 
Address         307 Waverley Oaks Road Suite 101 Waltham, MA 02452, USA
Telephone       1-617-851-3769
Fax             1-617-812-6426
Email           rleblanc@correlagen.com
URL             www.correlagen.com
Method          Direct sequencing; Additionally we offer carrier testing 
Method          and known mutation analysis
Frequency       As needed
Turnaround      2-4 weeks
Price           Available upon request
Comment         Correlagen Diagnostics, Inc. is a CLIA certified and CAP
Comment         accredited clinical laboratory in United States. Our
Comment         company’s mission is to promote use of clinically
Comment         appropriate genetic testing to facilitate the diagnosis and
Comment         treatment of Primary Immunodeficiency Diseases. We offer
Comment         high-quality, cost-effective, full-length gene sequencing
Comment         tests, with rapid turn-around times and comprehensive and
Comment         user-friendly reporting.
//
Disease         X-linked lymphoproliferative syndrome (Duncan disease)
Accession       I0247
Date            08-Feb-2008 (Rel. 1, Created)
Date            08-Feb-2008 (Last updated)
IDR fact file   FF73.xml
OMIM            300490
Gene            SH2D1A
IDbase          SH2D1Abase
Contact         Romina LeBlanc, M.S., MBA
Address         Correlagen Diagnostics, Inc.
Address         307 Waverley Oaks Road Suite 101 Waltham, MA 02452, USA
Telephone       1-617-851-3769
Fax             1-617-812-6426
Email           rleblanc@correlagen.com
URL             www.correlagen.com
Method          Direct sequencing; Additionally we offer carrier testing 
Method          and known mutation analysis
Frequency       As needed
Turnaround      2-4 weeks
Price           Available upon request
Comment         Correlagen Diagnostics, Inc. is a CLIA certified and CAP
Comment         accredited clinical laboratory in United States. Our
Comment         company’s mission is to promote use of clinically
Comment         appropriate genetic testing to facilitate the diagnosis and
Comment         treatment of Primary Immunodeficiency Diseases. We offer
Comment         high-quality, cost-effective, full-length gene sequencing
Comment         tests, with rapid turn-around times and comprehensive and
Comment         user-friendly reporting.
//
Disease         CD8alpha deficiency
Accession       I0248
Date            11-Feb-2008 (Rel. 1, Created)
Date            11-Feb-2008 (Last updated)
IDR fact file   FF64.xml
OMIM            186910
Gene            CD8A
IDbase          CD8Abase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is  
Price           required for participants of the german health insurance  
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         X-linked SCID(gammac-chain deficiency)
Accession       I0249
Date            11-Feb-2008 (Rel. 1, Created)
Date            11-Feb-2008 (Last updated)
IDR fact file   FF8.xml
OMIM            308380 
Gene            IL2RG
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is  
Price           required for participants of the german health insurance  
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         IL2RA deficiency/IL2RA
Accession       I0250
Date            11-Feb-2008 (Rel. 1, Created)
Date            11-Feb-2008 (Last updated)
IDR fact file   FF63.xml
OMIM            147730
Gene            IL2RA
IDbase          IL2RAbase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is  
Price           required for participants of the german health insurance  
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//
Disease         Griscelli syndrome, type 3 /MLPH
Accession       I0251
Date            11-Feb-2008 (Rel. 1, Created)
Date            11-Feb-2008 (Last updated)
IDR fact file   FF156.xml
OMIM            606526
Gene            MLPH
IDbase          MLPHbase
Contact         Dr. Klaus Schwarz
Address         Institute for Clinical Transfusion Medicine and 
Address         Immunogenetics (IKT), Ulm, Helmholtzstrasse 10, 89081 Ulm, 
Address         Germany
Telephone       +49 731 150 599
Fax             +49 731 150 645
Email           klaus.schwarz@uni-ulm.de
Method          Direct sequencing
Frequency       on demand
Price           international: on request / an Überweisungsschein is 
Price           required for participants of the german health insurance 
Price           system
Comment         Samples: In general 1-5 ml EDTA blood. In specific cases
Comment         after discussion additional blood or tissue components may
Comment         be required.
//