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 - databases for immunodeficiency-causing variations

   CD40Lbase
   Variation registry for  X-linked Hyper-IgM syndrome (XHIM)


Aminoacid substitutions - CD40Lbase

 - indicates amino acid change that require more complex mutation than single nucleotide substitution.
Aminoacid substitutions
Hydrophilic
HydrophobicAcidicBasicPolarSpecial
--> AFILMVWYDEHKRNQSTCGPTotal
A ------34------18
F -11------------2
I ----------0
L ------7---815
M --------2------2
V 1--21---------4
W -----------2---22-6
Y ------2---1--3--6
D ------------0
E ------------1-1
H ------1--1----2
K --------1-2---3
R --1-----1
N ------------0
Q --------4-----4
S 1------1-2
T -1-10------1---12
C -------------0
G 2----1-12--4--1--11
P ------------0
Total 313110101870114208253979
Aminoacid substitutions (%)
Hydrophilic
HydrophobicAcidicBasicPolarSpecial
--> AFILMVWYDEHKRNQSTCGPTotal
A ------3.85.1------1.310.1
F -1.31.3------------2.5
I ----------0.0
L ------8.9---10.119.0
M --------2.5------2.5
V 1.3--2.51.3---------5.1
W -----------2.5---2.52.5-7.6
Y ------2.5---1.3--3.8--7.6
D ------------0.0
E ------------1.3-1.3
H ------1.3--1.3----2.5
K --------1.3-2.5---3.8
R --1.3-----1.3
N ------------0.0
Q --------5.1-----5.1
S 1.3------1.3-2.5
T -1.3-12.7------1.3---15.2
C -------------0.0
G 2.5----1.3-1.32.5--5.1--1.3--13.9
P ------------0.0
Total 3.81.33.81.312.71.30.01.310.18.90.01.317.72.50.010.12.56.33.811.4100.0