ID-bases-logo
 - databases for immunodeficiency-causing variations

   ELA2base
   Variation registry for  Cyclic neutropenia; Congenital neutropenia


Aminoacid substitutions - ELA2base

 - indicates amino acid change that require more complex mutation than single nucleotide substitution.
Aminoacid substitutions
Hydrophilic
HydrophobicAcidicBasicPolarSpecial
--> AFILMVWYDEHKRNQSTCGPTotal
A ----12--1-----3-218
F -1------------1
I -1------1---2
L -10---1-----415
M ---1-----------1
V 14--1---------6
W ---------------0
Y -------------0
D ------------0
E -------------0
H ---1---------1
K ------------0
R -------22224
N ------------0
Q -------------0
S 110-------11
T -----------0
C -----3----1--2--6
G ----1-12--5----9
P --10-------1---11
Total 011122514033210702224008105
Aminoacid substitutions (%)
Hydrophilic
HydrophobicAcidicBasicPolarSpecial
--> AFILMVWYDEHKRNQSTCGPTotal
A ----11.4--1.0-----2.9-1.917.1
F -1.0------------1.0
I -1.0------1.0---1.9
L -9.5---1.0-----3.814.3
M ---1.0-----------1.0
V 1.03.8--1.0---------5.7
W ---------------0.0
Y -------------0.0
D ------------0.0
E -------------0.0
H ---1.0---------1.0
K ------------0.0
R -------21.01.922.9
N ------------0.0
Q -------------0.0
S 1.09.5-------10.5
T -----------0.0
C -----2.9----1.0--1.9--5.7
G ----1.0-1.01.9--4.8----8.6
P --9.5-------1.0---10.5
Total 0.010.51.021.04.813.30.02.92.91.91.00.06.70.021.01.93.80.00.07.6100.0