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This dataset consists of somatic variations leading to amino acid substitutions and that lead to loss of protein activity in tumours. It is a subset of variation dataset available in Curated TP53 database (Tumors only).
This dataset consists of somatic variations leading to amino acid substitutions that are annotated as pathogenic in ClinVar database.
DoCM validated cancer variations
This dataset consists of validated cancer variations leading to amino acid substitutions. It is a subset of the dataset available in Database of Curated Mutations (DoCM).
Reference: Niroula A, Vihinen M (2015) Harmful somatic amino acid substitutions affect key pathways in cancers.BMC Med Genomics 8:53. PUBMED
Last updated: 2015-07-08 by Gerard Schaafsma.