A benchmark database for variations

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1. Variation datasets affecting protein tolerance

PredictSNP benchmark datasets

These datasets were developed and used for the evaluation of selected prediction tools and for training of the consensus classifier PredictSNP. A detailed description of the datasets can be found in the publication mentioned below. The sets are:

Bendl J, Stourac J, Salanda O, Pavelka A, Wieben E, Zendulka J, Brezovsky J and Damborsky J, 2014.
PredictSNP: Robust and accurate consensus classifier for prediction of disease-related mutations.
PLoS Comput Biol 10(1): e1003440. doi:10.1371/journal.pcbi.1003440   PUBMED