PON-mt-tRNA

PON-mt-tRNA is a posterior probability-based method for classification of mitochondrial tRNA variations. It integrates machine learning-based probability of pathogenicity and evidence-based likelihood of pathogenicity to predict the posterior probability of pathogenicity. In absence of evidence, it classifies the variations based on the machine learning-based probability of pathogenicity. It is trained and tested on variants classified as definitely pathogenic and definitely neutral by Yarham et al..
A manuscript describing PON-mt-tRNA has been published in Nucleic Acids Research.

'
Home About Disclaimer Datasets

Disclaimer

This non-profit server, its associated data and services are for research purposes only. The responsibility of Protein Structure and Bioinformatics Group, Lund University is limited to applying the best efforts in providing and publishing good programs and data. The developers have no responsibility for the usage of results, data or information which this server has provided.



Liability

In preparation of this site and service, every effort has been made to offer the most current and correct information possible. We render no warranty, express or implied, as to its accuracy or that the information is fit for a particular purpose, and will not be held responsible for any direct, indirect, putative, special, or consequential damages arising out of any inaccuracies or omissions. In utilizing this service, individuals, organizations, and companies absolve Lund University or any of their employees or agents from responsibility for the effect of any process, method or product or that may be produced or adopted by any part, notwithstanding that the formulation of such process, method or product may be based upon information provided here.